Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells [PDF]
In patients with bile acid malabsorption, high concentrations of bile acids enter the colon and stimulate Cl− and fluid secretion, thereby causing diarrhoea. However, deoxycholic acid (DCA), the predominant colonic bile acid, is normally present at lower
Alan F. Hofmann+45 more
core +1 more source
Association of diverse bacterial communities in human bile samples with biliary tract disorders: a survey using culture and polymerase chain reaction-denaturing gradient gel electrophoresis methods [PDF]
Bacterial infection is considered a predisposing factor for disorders of the biliary tract. This study aimed to determine the diversity of bacterial communities in bile samples and their involvement in the occurrence of biliary tract diseases. A total of
Alebouyeh, M.+5 more
core +1 more source
Biliary Tract Carcinogenesis Model Based on Bile Metaproteomics
Purpose: To analyze human and bacteria proteomic profiles in bile, exposed to a tumor vs. non-tumor microenvironment, in order to identify differences between these conditions, which may contribute to a better understanding of pancreatic carcinogenesis ...
Ariel A. Arteta+8 more
doaj +1 more source
Indomethacin decreases viscosity of gallbladder bile in patients with cholesterol gallstone disease [PDF]
There is experimental evidence that inhibition of cyclooxygenase with nonsteroidal anti-inflammatory drugs may decrease cholesterol gall-stone formation and mitigate biliary pain in gall-stone patients.
Brandl, H.+8 more
core +1 more source
Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance [PDF]
Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases. Ideally, room temperature stable dry formulations of live bacterial vaccines will allow oral vaccination ...
Edwards, Alexander D.+1 more
core +1 more source
The elucidation of the molecular basis of the rare disease, sitosterolemia, has revolutionized our mechanistic understanding of how dietary sterols are excreted and how cholesterol is eliminated from the body.
Shailendra B. Patel+2 more
doaj
An approximate cooperativity analysis by DSC of phase transitions of DPPC-DOCNa dispersions [PDF]
The effect of solute, sodium deoxycholate bile salt (DOCNa), on the cooperativity of ordered-fluid, fosfolipid phase transition has been investigated by determining of the transition widths in multibilayer dispersions of the dipalmitoylphosphatidylcholine (DPPC)-DOCNa mixtures. The DT1/2 values were determined by differential scanning calorimetry.
arxiv
The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A.+8 more
core +1 more source
Wandering ascaris coming out through the abdominal wall
A rare case of ascaris coming out through the anterior abdominal wall is reported here. A 40-year-old female had undergone dilatation and curettage by a quack. On the second day she presented with presented with features of peritonitis. She was explored.
Mohd L Wani+7 more
doaj
Unclassified autoimmune pancreatitis mimicking pancreatic cancer [PDF]
A 24-year-old black male presented with a 1-week obstructive jaundice and intermittent abdominal pain, with no significant weight loss and an unsuspicious abdominal exam.
Alves, A+3 more
core +1 more source