Results 161 to 170 of about 26,722 (309)

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

Journal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios, Stavros P. Papadakos, Alexandros Ioannou, Maximos Frountzas, Dimosthenis Michelakis, Dimitrios Patsouras, Spyridon Dritsas, Manousos‐Georgios Pramateftakis, Dimitrios Schizas   +8 more
wiley   +1 more source

Dietary Fiber Regulation of Gut Microbiota and Bile Acid Metabolism in Animals: Implications for Animal Nutrition. [PDF]

Vet Sci
Lai J, Zentek J, Grześkowiak ŁM.
europepmc   +1 more source

Tu1123 Acid and Bile Salts Activate Hypoxia Inducible Factor (HIF)-2α and Increase Transcription of HIF-Target PRO-Inflammatory Cytokines in Esophageal Squamous Cell Lines: A Potential Mechanism for the Pathogenesis of Reflux Esophagitis

, 2012
Xiaofang Huo, Qiuyang Zhang, Chunhua Yu, Xi Zhang, Edaire Cheng, David H. Wang, Stuart J. Spechler, Rhonda F. Souza   +7 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Medium-chain triglyceride supplementation in infants with biliary atresia: a review of the evidence for impacts on fat absorption, growth, nutritional status and clinical outcomes. [PDF]

Proc Nutr Soc
Mancell S, Dhawan A, Ayis S, Whelan K.
europepmc   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Probiotic characterization and spore production optimization of Lysinibacillus sp. MK212927. [PDF]

Appl Microbiol Biotechnol
El-Sayed SE, Messiha AA.
europepmc   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, EarlyView.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

The Probiotic Effects of <i>Lactobacillus intestinalis</i> Y10 Isolated From Feces of Wild Brown Rat (<i>Rattus norvegicus</i>). [PDF]

Int J Microbiol
Yu S, Hong P, Wang CM, Chou S, Lai CH.
europepmc   +1 more source

Comparative studies of ‘bile salts’. 11. 3α:6α:12α-Trihydroxycholanic acid and related substances [PDF]

, 1958
G. A. D. Haslewood
openalex   +1 more source