Results 191 to 200 of about 29,638 (318)

Drug Survival of Drugs Recommended for Irritable Bowel Syndrome: A Retrospective Observational Study

open access: yesNeurogastroenterology &Motility, EarlyView.
ABSTRACT Background There is limited data on how drugs prescribed for functional bowel disorders are re‐prescribed in clinical practice. This study aimed to investigate drug survival rates of different irritable bowel syndrome (IBS) treatments among patients referred to a gastroenterologist.
Alice Sandberg‐Janzon, Pontus Karling
wiley   +1 more source

Inhibition of hepatic bile salt uptake by Bulevirtide reduces atherosclerosis in Oatp1a1−/− Ldlr−/− mice

open access: yesJournal of Lipid Research
Bile salts can strongly influence energy metabolism through systemic signaling, which can be enhanced by inhibiting the hepatic bile salt transporter Na+ taurocholate cotransporting polypeptide (NTCP), thereby delaying hepatic reuptake of bile salts to ...
Begoña Porteiro   +12 more
doaj  

Changing Gastrointestinal Transit Time Alters Microbiome Composition and Bile Acid Metabolism: A Cross‐Over Study in Healthy Volunteers

open access: yesNeurogastroenterology &Motility, EarlyView.
Alterations in whole gut transit time (WGTT) significantly impact microbiome composition and bile acid metabolism. Using senna and loperamide, we show that WGTT changes influence bacterial diversity, bile acid profiles, and fibroblast growth factor 19, with effects reversing after 16 days—highlighting the dynamic gut‐microbiome‐bile acid interplay ...
Evette B. M. Hillman   +11 more
wiley   +1 more source

The Role of Intestinal Microbiota and Dietary Fibre in the Regulation of Blood Pressure Through the Interaction with Sodium: A Narrative Review. [PDF]

open access: yesMicroorganisms
Rudzka A   +6 more
europepmc   +1 more source

A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease

open access: yesNeurogastroenterology &Motility, EarlyView.
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech   +4 more
wiley   +1 more source

ASBT governs neonatal bile acid homeostasis early in life despite its strong ileal repression. [PDF]

open access: yesAm J Physiol Gastrointest Liver Physiol
Morales Aparicio J   +9 more
europepmc   +1 more source

Frequency and Severity of Hyperbilirubinemia in Cats and Dogs With Septic Peritonitis or Pyothorax

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To characterize serum total bilirubin (TBil) value within 72 h of admission in cats and dogs with septic peritonitis or pyothorax and its relationship with outcome. Design Cross‐sectional retrospective study. Setting University teaching hospital.
Frederick John Benham‐Crosswell   +3 more
wiley   +1 more source

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