Results 121 to 130 of about 44,525 (313)

Intraductal Papillary Neoplasms of the Bile Duct: Clinical Case Insights and Literature Review

Clinics and Practice
Background: Intraductal papillary neoplasms of the bile duct (IPNB) are rare precancerous lesions with implications for the development of cholangiocarcinoma (CCA). Recognizing IPNB and managing its recurrence pose challenges in clinical practice.
Luca Toti, Tommaso Maria Manzia, Francesca Di Giuliano, Eliseo Picchi, Laura Tariciotti, Domiziana Pedini, Luca Savino, Giuseppe Tisone, Roberta Angelico   +8 more
doaj   +1 more source

Bile Duct Neoplasm [PDF]

, 2020
openaire   +1 more source

Mucin hypersecreting bile duct neoplasm

Tropical Gastroenterology, 2016
Balbir, Singh, Vivek, Aery, Mahendra Jagannath, Parage   +2 more
openaire   +2 more sources

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Clinical Features, Differential Diagnosis and Treatment of IgG₄-Related Sclerosing Cholangitis

Архивъ внутренней медицины
The aim: To present the state-of-the-art of clinical features, differential diagnosis and treatment of IgG4-related sclerosing cholangitis.Key points: IgG4-sclerosing cholangitis is a fibrotic inflammatory disease affecting the intrahepatic and ...
A. K. Guseva, A. V. Okhlobystin
doaj   +1 more source

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

iMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng, Huiying Liu, Sizhe Chen, Jianhui Gu, Sisi Cai, Xiang Liu, Raphaela I. Lau, Yao Zhang, Sunjae Lee, Xiaoyan Wang, Kewei Fan, Xiaole Yin, Hein Min Tun, Renyou Gan, Haichong Wu, Qi Su   +15 more
wiley   +1 more source

Two stable gut microbiome guilds predict liver tumor class and treatment responses

iMeta, EarlyView.
Gut microbiome alterations are linked to hepatocellular carcinoma (HCC), yet taxon‐based biomarkers often lack reproducibility. Using shotgun metagenomics from 120 resectable HCC (MT) and 76 benign hepatic tumor controls (BT), we reconstructed a stable interaction‐based Two Competing Guilds model (HCC‐TCG) comprising 142 genomes organized into two ...
Yang Liu, Zefan Zhang, Guojun Wu, Bowen Li, Linghua Wang, Jincheng Wang, Zixian Wei, Zhiyue Wang, Jinhua Yang, Kunyu Zhang, Tianqi Zhang, Xin Tao, Tao Chen, Jia Fan, Jian Zhou, Xinrong Yang, Liping Zhao, Yunwei Wei   +17 more
wiley   +1 more source

Intratumoral Enterobacter hormaechei drives gemcitabine resistance in pancreatic cancer via cddL‐mediated drug inactivation

iMeta, EarlyView.
Gemcitabine resistance poses a critical barrier to improving survival in pancreatic cancer, yet the microbial drivers remain elusive. By integrating 16S rRNA amplicon sequencing with large‐scale culturomics across 114 clinical samples, we identified Enterobacter hormaechei as a key intratumoral pathogen. We demonstrate that E.
Jun‐Feng Peng, Meixia Li, Ting Niu, Judong Li, Wei Niu, Minghui Zheng, Quanjiang Ji, Chuan Li, Chenghao Shao, Kan Ding   +9 more
wiley   +1 more source

Laparoscopic Resection of Caudate Lobe Liver Tumors in Clinical Practice

iNew Medicine, EarlyView.
ABSTRACT The caudate lobe (Couinaud segment I), owing to its deep location in the posterosuperior liver, intimate encirclement by the inferior vena cava (IVC), and close adjacency to the hepatic hilum and major hepatic veins, presents a formidable anatomical challenge for resection.
Dingde Ye, Wenjie Zhang, Qiaoyu Liu, Beicheng Sun, Qingxiang Xu   +4 more
wiley   +1 more source

Extrahepatic Bile Duct Neoplasm [PDF]

, 2020
openaire   +1 more source