Results 131 to 140 of about 38,616 (261)

Delayed Bile Duct Injury Preceded by Sepsis After Biliary Cooling-Assisted Ablation of Hilar Hepatocellular Carcinoma. [PDF]

open access: yesACG Case Rep J
Tarumi C   +17 more
europepmc   +1 more source

Socioeconomic Inequalities in Receipt of Curative‐Intent Treatment and Survival After Surveillance‐Detected Hepatocellular Carcinoma: A Nationwide Cohort Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Socioeconomic inequalities in receipt of curative‐intent treatment and survival persist among individuals with surveillance‐detected HCC within a universal healthcare system. These findings suggest that surveillance alone is insufficient to ensure equitable outcomes and highlight the need for strategies addressing social determinants across the care ...
Hannes Hagström   +6 more
wiley   +1 more source

Synchronous Intra-ampullary Papillary-Tubular Neoplasm and Gallbladder Cancer. [PDF]

open access: yesCureus
Suto K   +11 more
europepmc   +1 more source

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy

open access: yesCancer Science, EarlyView.
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley   +1 more source

Organ‐Specific Cancer‐Associated Fibroblast Subtypes Across the Digestive System Linked to Cancer Hallmarks

open access: yesCancer Science, EarlyView.
We integrated 14 single‐cell RNA‐seq datasets and 18 bulk cohorts to define eight CAF subtypes in GI cancers. myCAF1 and myCAF2 promoted immunosuppressive, poor‐prognosis niches, whereas iCAF1 was linked to favorable prognosis and antitumor immunity.
Huaitao Wang   +7 more
wiley   +1 more source

Primary Extrahepatic Biliary Mucinous Cystic Neoplasm Suspected Preoperatively and Treated by Robotic Pancreaticoduodenectomy: A Case Report. [PDF]

open access: yesSurg Case Rep
Shimogata Y   +13 more
europepmc   +1 more source

Bile‐Derived Exosomal miR‐196a/‐196b as Diagnostic Biomarkers Associated With Tumor Progression in Biliary Tract Cancer

open access: yesCancer Science, EarlyView.
Bile‐derived exosomal miR‐196a and miR‐196b are identified as novel biomarkers for biliary tract cancer. Serum miR‐196a levels are significantly elevated in advanced disease with metastasis, while both miRNAs contribute to tumor progression by promoting cancer cell proliferation and invasion.
Naotaka Kugiyama   +20 more
wiley   +1 more source

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