Results 101 to 110 of about 23,822 (250)

Indoleamine 2,3‐Dioxygenase 1 as an Adjunctive Histopathological Marker of Cholangitis Activity in Primary Biliary Cholangitis

Hepatology Research, EarlyView.
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura, Shinji Shimoda, Ryoka Masuda, Tram Nguyen Thi, Rui Yang, Quynh Nguyen Thi, Dong Le Thanh, Yuko Tamano, Yasunori Sato, Taro Yamashita, Kenichi Harada   +10 more
wiley   +1 more source

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

Intrahepatic Bile Duct [PDF]

, 2020
openaire   +1 more source

How to Do a Laparoscopic Left Hepatectomy for Cystic Lesions Compressing the Middle Hepatic Vein: The Hemodynamic Advantage of Pneumoperitoneum

ANZ Journal of Surgery, EarlyView.
Jonathan Ben Daniel, Krishna Kotecha, Kai Brown, Anubhav Mittal, Jaswinder Samra   +4 more
wiley   +1 more source

Intratumoral IDH1 mutation status in intrahepatic cholangiocarcinoma is homogeneous

Histopathology, EarlyView.
IDH1 mutations are spatially homogeneous in intrahepatic cholangiocarcinoma. Single‐sample molecular testing is sufficient for clinical decision‐making. Introduction IDH1 mutations occur in approximately 10%–20% of intrahepatic cholangiocarcinoma (iCCA) and constitute an established target for molecularly guided therapy.
Sharon Weidmann, Silvana Ebner, Aayushi Srivastava, Armin Wiegering, Stefan Zeuzem, Peter J. Wild, Maximilian N. Kinzler, Melanie C. Winter, Dirk Walter   +8 more
wiley   +1 more source

Intraoperative cholangiography during open cholecystectomy in 73 dogs with benign gallbladder disease

Veterinary Surgery, EarlyView.
Abstract Objective To evaluate intraoperative cholangiography (IOC) during open cholecystectomy in dogs with benign gallbladder disease, including cases with preoperative common bile duct (CBD) obstruction, and to describe the short‐term outcomes. Study design Retrospective case series. Animals A total of 73 client‐owned dogs.
Ryusei Konno, Yasuyuki Kaneko, Misaki Matsunaga, Tatsuyuki Osuga, Ryota Okadera, Shidow Torisu, Shushi Yamamoto, Kiyokazu Naganobu   +7 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles   +3 more
wiley   +1 more source

Anatomic Variation of the Intrahepatic Bile Duct

Internal Medicine, 2008
Uchiyama, Daiji, Fujimoto, Kiminori, Fujimoto, Naoko, Hayabuchi, Naofumi   +3 more
openaire   +3 more sources

Phase I/II Prospective Study on Endoscopic Ultrasound‐Guided Hepaticogastrostomy as Primary Drainage for Unresectable Malignant Hilar Biliary Obstruction

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Various drainage methods have been used for unresectable malignant hilar biliary obstruction (MHBO). However, controlling cholangitis and obstructive jaundice is still challenging. We performed a phase I/II study of endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) as primary drainage for MHBO.
Tomoki Ogata, Kazuo Hara, Nozomi Okuno, Shin Haba, Takamichi Kuwahara, Shimpei Matsumoto, Hiroki Koda, Keigo Oshiro   +7 more
wiley   +1 more source

Mechanism of Fibrotic Anastomosis Formation in Endoscopic Ultrasound‐guided Hepaticogastrostomy Using a Plastic Stent: Insights From an Autopsy Case of Perihilar Cholangiocarcinoma

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) is an established alternative to other biliary drainage techniques for treating malignant biliary obstruction. Although the anastomosis created by EUS‐HGS is believed to mature within several weeks, histopathological evidence supporting this assumption remains limited, particularly in ...
Kosuke Maehara, Junji Mitsushita, Tomoyoshi Shida, Kazuki Hirano, Daisuke Hattori, Yoshiki Sato, Rikako Koyama, Yasuro Miura, Yutaka Takazawa, Tsunao Imamura   +9 more
wiley   +1 more source