Results 101 to 110 of about 22,949 (221)

Clinical Utility and Safety of a Novel Ultraslim Catheter‐Type Peroral Cholangioscope/Pancreatoscope: A Single‐Center Case Series

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Peroral cholangioscopy (POCS) and peroral pancreatoscopy (POPS) enable direct intraductal visualization for pancreatobiliary disease diagnosis and management. Nonetheless, conventional devices have relatively large diameters, limiting their use in narrow ducts.
Hiroyuki Kojima   +13 more
wiley   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley   +8 more
wiley   +1 more source

Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar   +9 more
wiley   +1 more source

Management of Satellite Lesions in Hepatocellular Carcinoma: An Updated Review

open access: yesJournal of Surgical Oncology, Volume 134, Issue 2, Page 157-165, August 2026.
ABSTRACT Satellite lesions, defined as microscopic or small macroscopic tumor nodules within 2 cm of a primary hepatocellular carcinoma (HCC), represent early intrahepatic dissemination and are strongly associated with aggressive tumor biology.
Andy Tran   +4 more
wiley   +1 more source

Anatomic Variation of the Intrahepatic Bile Duct

open access: yesInternal Medicine, 2008
Uchiyama, Daiji   +3 more
openaire   +3 more sources

Machine Learning Predicts Treatment Response and Prognostic Pathways From Whole‐Blood Transcriptome in Primary Biliary Cholangitis

open access: yesLiver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Prognostic biomarkers that link disease progression and/or responses to therapeutic interventions in patients with primary biliary cholangitis (PBC) remain undefined. In this study, we used a machine learning (ML) approach with whole‐blood transcriptomic data to predict clinical outcomes in response to obeticholic acid (OCA)
Hussain Syed   +10 more
wiley   +1 more source

Prognostic Impact of Concomitant Genomic Alterations in FGFR2‐Positive Cholangiocarcinoma Treated With Pemigatinib

open access: yesLiver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background & Aims Anti‐FGFR therapies changed the treatment landscape for patients with previously treated, advanced, or metastatic cholangiocarcinoma (CCA) harbouring FGFR2 fusions/rearrangements. However, primary resistance to FGFR inhibitors remains a key challenge. In the present real‐world study, we aimed to evaluate the prognostic impact
Carolina Liguori   +45 more
wiley   +1 more source

Life Course Trajectories of Body Mass Index and Risk of Cancer in Adulthood: Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Objective This systematic review and meta‐analysis aimed to identify common life‐course body mass index (BMI) trajectories (childhood/adulthood to adulthood) and their impact on risk of cancer overall and cancer at different sites in adulthood. Methods Observational studies were identified that assessed the association of BMI trajectories with
Samira Behboudi‐Gandevani   +6 more
wiley   +1 more source

Gut‐Derived Sodium Butyrate Attenuates Liver Fibrosis by Inhibiting Aerobic Glycolysis via the HDAC3/c‐Myc Signaling Axis

open access: yesThe FASEB Journal, Volume 40, Issue 14, 31 July 2026.
This study explores the molecular mechanisms by which NaB ameliorates liver fibrosis from the perspectives of the gut–liver axis and metabolic reprogramming. In vivo and in vitro experiments demonstrate that gut‐derived NaB may alleviate liver injury and fibrosis by inhibiting hepatic stellate cell activation and aerobic glycolysis through the HDAC3/c ...
Yong Sun   +8 more
wiley   +1 more source

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