Results 131 to 140 of about 24,512 (278)

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Biliary differentiation and bile duct morphogenesis in development and disease.

, 2009
The biliary tract consists of a network of intrahepatic and extrahepatic ducts that collect and drain the bile produced by hepatocytes to the gut. The bile ducts are lined by cholangiocytes, a specialized epithelial cell type that has a dual origin ...
Carpentier, Rodolphe, Lemaigre, Frédéric P, Raynaud, Peggy, Antoniou, Aline, Lemaigre, Frédéric   +4 more
core   +1 more source

Intestinal type cholangiocarcinoma of intrahepatic large bile duct associated with hepatolithiasis--a new histologic subtype for further investigation.

, 2002
Intestinal metaplasia is regarded as a possible predisposing factor of cancer, particularly of the intestinal type adenocarcinoma. The clinicopathologic features of intestinal type adenocarcinoma have been well documented in the stomach, and intestinal ...
박영년, 박찬일
core  

Reframing Wnt/β‐Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley   +1 more source

Spontaneous rupture of intrahepatic biliary ducts with biliary peritonitis

, 2007
Spontaneous rupture of intrahepatic biliary ducts is a rare cause of acute abdomen due to biliary peritonitis. We report a 92-year-old woman with 48-h history of upper abdominal pain, nausea and vomiting, and peritoneal signs.
Yazici P., Aydin U., Coker A.
core  

Mortality Attributable to Hepatitis B and C in Italy, Romania, and Spain, 2022 Estimates

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Reliable data on viral hepatitis–related deaths remain limited, challenging assessment of progress towards the WHO elimination targets for mortality. To address this gap, we estimated hepatitis B‐ and C‐attributable mortality in Italy, Romania, and Spain for 2022.
Oleksandr Korotych, Helene Høgsbro Thygesen, Otilia Mårdh, Juliana Reyes‐Urueña, Gaetano Marrone, Jürgen Rockstroh, Marie‐Louise Jakobsen, Catherine de Martel, Loreta A. Kondili, Maria Giovanna Quaranta, Benedetta Mattioli, Stefano Rosato, Maria Rendina, Antonella De Feudis, Valentina Cossiga, Simona Albano, Filomena Morisco, Mauro Viganò, Alessandro Loglio, Stefano Fagiuoli, Vincenza Calvaruso, Ciro Celsa, Francesco Longobardi, Roberta Coppola, Francesco Paolo Russo, Sara Battistella, Nicola Coppola, Caterina Sagnelli, Barbara Coco, Maurizia Rossana Brunetto, Odette Popovici, Denisa Janță, Cristian Calomfirescu, Liana Simona Gheorghe, Mihaela Ghioca, Carmen Ester, Mirela Chitul, Razvan Cerban, Anca Trifan, Laura Huiban, Cristina Muzica, Alina Popescu, Roxana Sirli, Camelia Nica, Alexandru Popa, Maria Buti Ferret, Elena Vargas‐Accarino, Asuncion Díaz, Catalina Fernández Méndez, Luis Morano, Sonia Alonso, Adriana Ahumada, Rafael Bañares Cañizares, Dorthe Raben, Erika Duffell   +54 more
wiley   +1 more source

Cholangitis resembling Caroli’s syndrome in a patient with autosomal dominant polycystic kidney disease: Case report

SAGE Open Medical Case Reports
Caroli’s syndrome is a rare autosomal recessive disorder characterized by segmental cystic dilation of the intrahepatic bile ducts and congenital hepatic fibrosis. It is associated with autosomal recessive polycystic kidney disease.
Maha Arkan Khudhair, Rikke Christensen, Anne Skakkebæk, Jakob Grue Graverholt, Anders Bergh Lødrup   +4 more
doaj   +1 more source

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

Congenital hepatic fibrosis with dilation of intrahepatic bile ducts. A therapeutic approach

, 1976
A case of congenital hepatic fibrosis with dilation of the intrahepatic ducts is presented. External drainage and lavage of the biliary tract through a prosthetic "Y" tube and internal drainage accomplished by a Roux en-Y cholangiojejunostomy resulted in
Glasser, K, Levi, J U, Schiff, E R, Dusol, Jr, M   +3 more
core   +1 more source

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

Advanced Science, Volume 13, Issue 32, 9 June 2026.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang, Jiahao Li, Zhuying Yue, Beixuan He, Wenhua Zhang, Zhen Fang, Qing Xia, Yingbin Liu, Yanjing Li   +8 more
wiley   +1 more source