Results 131 to 140 of about 60,633 (308)
Crosstalk of liver, bile ducts and the gut [PDF]
, 2009 A complex interplay of liver, bile ducts, and the gut critically determines functioning of these organs in health and disease. Biochemical and physiological aspects of their interaction and the role of inflammatory cells, cytokines, bile acids, visceral ...
Beuers, Ulrich
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Clinical Pharmacology &Therapeutics, EarlyView.Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu +6 more
wiley +1 more source
Mass-forming intrahepatic cholangiocarcinoma presenting with painful obstructive hemobilia
Journal of the Belgian Society of Radiology, 2014 We report a very rare case of acute obstructive hemobilia caused by bleeding of a mass-forming intrahepatic cholangiocarcinoma in a 75-year old man. The prompt complete emergency diagnosis was made by ultrasound and confirmed by MDCT.
B Coulier +3 more
doaj +1 more source
Iatrogenic Lesions of the Extrahepatic Bile Ducts during Laparoscopic Cholecystectomy [PDF]
, 2017 Introduction: Laparoscopic cholecystectomy is the gold standard in the treatment of gallstones. However, this surgical approach is also associated with potential complications.
Taseva, A. +6 more
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Clinical Pharmacology &Therapeutics, EarlyView.Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving supratherapeutic OCA doses (100–250 mg).
Abigail K. Mayo +4 more
wiley +1 more source
Six Rare Biliary Tract Anatomic Variations: Implications for Liver Surgery
Eurasian Journal of Medicine, 2011 Objective: The variations in the anatomy of the biliary tract need to be recognized in modern liver surgery. The purpose of this clinical and anatomical study is to describe several novel biliary tract variations and to outline their practical importance
Daniel V. Kostov, Georgi L. Kobakov
doaj
Clinical Case Reports, 2018 Key Clinical Message Aberrant subvesical bile ducts are rare anatomical structures. Damage to these ducts leads to bile leakage and can result in life‐threatening complications.
Sanghyun Song, Sungho Jo
doaj +1 more source
Introduction Imaging of Diseases of the Bile Ducts and Gallbladder [PDF]
, 2020 Diagnostic imaging plays a key role in the management of diseases of the bile ducts and gallbladder. Although ultrasonography (US) remains the first-line imaging modality for suspected biliary obstruction and even the standard of reference for ...
C D Becker
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Clinical Pharmacology &Therapeutics, EarlyView.Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian +12 more
wiley +1 more source
Immunohistochemical localization of truncated midkine in developing human bile ducts [PDF]
, 2003 Midkine (MK) is a heparin-binding growth factor whose gene has been identified in embryonal carcinoma cells in early stages of retinoic acid-induced differentiation. In the present study, we investigated the developmental localization of truncated MK
Terada, T. +3 more
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