Results 121 to 130 of about 60,593 (309)

Functional anatomy of normal bile ducts.

open access: yes, 2008
The biliary tree is a complex network of conduits that begins with the canals of Hering and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to
FABRIS, LUCA, STRAZZABOSCO M
core  

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin   +7 more
wiley   +1 more source

Six Rare Biliary Tract Anatomic Variations: Implications for Liver Surgery

open access: yesEurasian Journal of Medicine, 2011
Objective: The variations in the anatomy of the biliary tract need to be recognized in modern liver surgery. The purpose of this clinical and anatomical study is to describe several novel biliary tract variations and to outline their practical importance
Daniel V. Kostov, Georgi L. Kobakov
doaj  

Peritonitis from injury of an aberrant subvesical bile duct during laparoscopic cholecystectomy: A rare case report

open access: yesClinical Case Reports, 2018
Key Clinical Message Aberrant subvesical bile ducts are rare anatomical structures. Damage to these ducts leads to bile leakage and can result in life‐threatening complications.
Sanghyun Song, Sungho Jo
doaj   +1 more source

Ltrasound Comparative Morphometry of Intra- And Extrahepatic Bile Ducts after Laparoscopic Cholecystectomy

open access: yes, 2023
The use of ultrasound examination of cholelithiasis allows you to make the correct diagnosis as soon as possible, determine the subsequent treatment tactics, morphological changes inside and extrahepatic ducts, and start conservative or surgical ...
M. M., Jumaeva, F. Kh., Akhmedov
core  

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu   +6 more
wiley   +1 more source

Errors and mistakes in the ultrasound diagnostics of the liver, gallbladder and bile ducts

open access: yes, 2012
Ultrasonography is the most widespread imaging technique used in the diagnostics of the pathologies concerning the organs in the abdominal cavity. Similarly to other diagnostic tools, errors may occur in ultrasound examinations.
Gierbliński, Ireneusz   +5 more
core  

Immunohistochemical localization of truncated midkine in developing human bile ducts [PDF]

open access: yes, 2003
Midkine (MK) is a heparin-binding growth factor whose gene has been identified in embryonal carcinoma cells in early stages of retinoic acid-induced differentiation. In the present study, we investigated the developmental localization of truncated MK
Terada, T.   +3 more
core  

Quantitative Systems Toxicology Model Predicts Obeticholic Acid‐Associated Liver Injury in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving supratherapeutic OCA doses (100–250 mg).
Abigail K. Mayo   +4 more
wiley   +1 more source

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