Results 31 to 40 of about 21,958 (289)

Multi-scale modeling of follicular ovulation as a reachability problem [PDF]

Multiscale Modeling & Simulation 6, 3 (2007) 895--912, 2006
During each ovarian cycle, only a definite number of follicles ovulate, while the others undergo a degeneration process called atresia. We have designed a multi-scale mathematical model where ovulation and atresia result from a hormonal controlled selection process.
arxiv   +1 more source

Identification of PKD1L1 Gene Variants in Children with the Biliary Atresia Splenic Malformation Syndrome [PDF]

, 2019
Biliary atresia (BA) is the most common cause of end‐stage liver disease in children and the primary indication for pediatric liver transplantation, yet underlying etiologies remain unknown.
Alonso, Estella M, Berauer, John‐Paul, Bezerra, Jorge A, Bull, Laura N, Chopra, Pankaj, Cutler, David J, Finegold, Milton J, Gibbs, Richard A, Guthery, Stephen L, Harpavat, Sanjiv, Hegde, Madhuri R, Kamath, Binita M, Karpen, Saul J, Loomes, Kathleen M, Magee, John C, Mezina, Anya I, Molleston, Jean P, Moore, Barry, Murray, Karen F, Muzny, Donna M, Network, for the Childhood Liver Disease Research, Okou, David T, Perlmutter, David H, Rajagopalan, Ramakrishnan, Rosenthal, Philip, Russo, Pierre, Sabo, Aniko, Sherker, Averell H, Sokol, Ronald J, Spinner, Nancy B, Squires, Robert H, Thompson, Richard J, Wang, Kasper S, Yandell, Mark   +33 more
core   +2 more sources

Association of Gut Microbiota and Metabolites With Disease Progression in Children With Biliary Atresia

Frontiers in Immunology, 2021
Background and AimsBiliary atresia is the most common cause of liver disease and liver transplantation in children. The accumulation of bile acids in hepatocytes and the stimulation of the intestinal microbiome can aggravate the disease progression. This
Wei Song, Wei Song, Li-Ying Sun, Li-Ying Sun, Li-Ying Sun, Zhi-Jun Zhu, Zhi-Jun Zhu, Lin Wei, Lin Wei, Wei Qu, Wei Qu, Zhi-Gui Zeng, Zhi-Gui Zeng, Ying Liu, Ying Liu, Hai-Ming Zhang, Hai-Ming Zhang, Wei Guo   +17 more
doaj   +1 more source

Weaning of immunosuppression in long - Term liver transplant recipients [PDF]

, 1995
Seventy-two long-surviving liver transplant recipients were evaluated prospectively, including a baseline allograft biopsy for weaning off of immunosuppression.
Abu-Elmagd, K, Demetris, AJ, Ebert, F, Flynn, B, Fung, JJ, McMichael, J, Ramos, H, Reinsmoen, N, Reyes, J, Starzl, TE, Tzakis, A, Zeevi, A   +11 more
core   +1 more source

Role of high-frequency linear probe in ultrasound diagnosis of biliary atresia

Medical Journal of Dr. D.Y. Patil University, 2014
Cause of cholestatic jaundice in early infancy continues to be a diagnostic dilemma, with biliary atresia being the most common cause. Increasing age is a negative prognostic factor for biliary atresia.
Sanjay Khaladkar, Pallavi J Agrawal, Vilas M Kulkarni, Amarjit Singh   +3 more
doaj   +1 more source

HIF-1alpha-pathway activation in cholangiocytes of patients with biliary atresia : an immunohistochemical/molecular exploratory study [PDF]

, 2023
Background: Biliary atresia is a neonatal disease characterized by choledochal obstruction and progressive cholangiopathy requiring liver transplantation in most patients. Hypoxia-ischemia affecting the biliary epithelium may lead to biliary obstruction.
Breton, Michèle Claire, Cerski, Carlos Thadeu Schmidt, Cipriano, Maria Augusta, Kieling, Carlos Oscar, Oliveira, Rui Caetano, Quelhas, Patrícia, Santos, Jorge Luiz dos, Shivakumar, Pranavkumar, Teixeira, Paulo, Verde, Ignacio, Vieira, Sandra Maria Gonçalves   +10 more
core  

Pediatric Liver Transplantation: Then and Now [PDF]

, 2020
This paper reviews the past 50 years of liver transplantation in children from the perspective of patient demographics, perioperative patient management, surgical techniques, immunosuppression and patient ...
Banh, DPT, Carullo, PC, Davis, PJ, Tran, LT, Vitu, C   +4 more
core   +1 more source

Biliary Atresia

Seminars in Pediatric Surgery, 2000
Although the prognosis of biliary atresia has been dramatically improved in the era of liver transplantation, the Kasai operation is still the first line of surgical treatment. Successful hepatic portoenterostomy depends on early diagnosis and surgery, adequate surgical technique, prevention of cholangitis, and precise postoperative management.
M, Nio, R, Ohi
openaire   +2 more sources

Biliary atresia: pathology, etiology and pathogenesis

Future Science OA, 2020
Biliary atresia is a progressive fibrosing obstructive cholangiopathy of the intrahepatic and extrahepatic biliary system, resulting in obstruction of bile flow and neonatal jaundice.
Mukul Vij, Mohamed Rela
doaj   +1 more source

Dynamic prediction and analysis based on restricted mean survival time in survival analysis with nonproportional hazards [PDF]

Computer Methods and Programs in Biomedicine. 2021, 207: 106155, 2021
In the process of clinical diagnosis and treatment, the restricted mean survival time (RMST), which reflects the life expectancy of patients up to a specified time, can be used as an appropriate outcome measure. However, the RMST only calculates the mean survival time of patients within a period of time after the start of follow-up and may not ...
arxiv   +1 more source