Results 11 to 20 of about 10,375 (181)
Novel NIR-II fluorescent probes for biliary atresia imaging
Acta Pharmaceutica Sinica B, 2023 Biliary atresia is a rare infant disease that predisposes patients to liver transplantation and death if not treated in time. However, early diagnosis is challenging because the clinical manifestations and laboratory tests of biliary atresia overlap with
Xiaodong Zeng +2 more
exaly +3 more sources
Nature Reviews Disease PrimersBiliary atresia (BA) is a progressive inflammatory fibrosclerosing disease of the biliary system and a major cause of neonatal cholestasis. It affects 1:5,000-20,000 live births, with the highest incidence in Asia. The pathogenesis is still unknown, but emerging research suggests a role for ciliary dysfunction, redox stress and hypoxia.
Siddiqui AI, Desai H, Ahmad T.
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Maternal risk factors for biliary atresia in neonates: a systematic review and meta-analysis [PDF]
Frontiers in PediatricsObjectiveThe risk factors for neonatal biliary atresia remain unclear. This study aimed to systematically analyze maternal risk factors associated with the development of neonatal biliary atresia (BA).MethodsA systematic search was conducted in PubMed ...
Ke Zhang, Zhu Chen
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대한영상의학회지, 2022 Biliary atresia is a progressive, idiopathic, obliterative disease of the extrahepatic biliary tree that presents with biliary obstruction in the neonatal period. It is the most common indication for liver transplantation in children.
Tae Yeon Jeon
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Japanese biliary atresia registry [PDF]
World Journal of Pediatric SurgeryThe Japanese Biliary Atresia Registry (JBAR) was launched in 1989 by the Japanese Biliary Atresia Society (JBAS) to investigate the epidemiology and etiology of biliary atresia and to improve surgical outcomes.
Masaki Nio +3 more
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Medisur, 2005 Biliary atresia is an obstructive and progressive process of unknown etiology that affects intra and/or extrahepatics biliary tracts and cause neonatal jaundice by serious obstruction of the biliary flow.
Miurkis Endis Miranda +2 more
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Organoids in biliary atresia. [PDF]
World J Pediatr SurgOrganoids are three-dimensional and self-organizing cell cultures of various lineages that resemble structures and functions of an organ in many ways, and they are versatile tools in disease modeling and patho-mechanistic study of human diseases affecting their tissues of origin.
Lui VCH.
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JHEP Reports, 2023 Background & Aims: Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare liver disease caused by biallelic variations in ABCB4. Data reporting on the impact of genotype and of response to ursodeoxycholic acid (UDCA) therapy on long ...
Emmanuel Gonzales +18 more
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Unveiling Hepatic Protein Alterations in Neonatal and Infant Biliary Atresia. [PDF]
Clin Pharmacol TherPediatric populations differ from adults in drug elimination capacity. While current scaling methods account for enzyme and transporter maturation, they overlook comorbidities, such as biliary atresia (BA), a liver disease appearing within the first 2–8 weeks of life that can progress to cirrhosis.
Al-Majdoub ZM +5 more
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Diagnostics, 2021 Biliary atresia is an aggressive liver disease of infancy and can cause death without timely surgical intervention. Early diagnosis of biliary atresia is critical to the recovery of bile drainage and long-term transplant-free survival.
Wenying Zhou, Luyao Zhou
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