Results 21 to 30 of about 10,375 (181)
Genetic Factors and Their Role in the Pathogenesis of Biliary Atresia
Frontiers in Pediatrics, 2022 Biliary Atresia, a common basis for neonatal cholestasis and primary indication for Liver Transplantation, accounts for 60% of pediatric Liver Transplantations.
Li-Na Wu +7 more
doaj +1 more source
Clinical Case Reports, 2023 Key Clinical Message A newborn with a rare form of biliary atresia had posterior fossa bleed and subarachnoid hemorrhage despite vitamin K prophylaxis, indicating biliary atresia is a causality rather than chance.
Susmin Karki +5 more
doaj +1 more source
Annals of Hepatology, 2021 Introduction and objectives: Differentiating biliary atresia from other causes of neonatal cholestasis is challenging, particularly when cytomegalovirus (CMV) and biliary atresia occur simultaneously.
Dongying Zhao +6 more
doaj +1 more source
Archives of Pediatric Gastroenterology, Hepatology, and Nutrition, 2022 Background: Biliary atresia (BA) is a progressive fibrosing obstructive cholangiopathy involving both the intrahepatic and extrahepatic biliary system; resulting in obstruction of bile flow and neonatal jaundice.
Ninung RD Kusumawati +5 more
doaj +1 more source
Early Living Donor Liver Transplant Is Associated With Improved Graft- and Patient-Survival Outcomes in Children With Biliary Atresia. [PDF]
Pediatr TransplantA proactive approach to living donor liver transplant in children with biliary atresia is associated with improved long‐term graft and patient survival. Low PELD living donor transplant should be considered to increase early transplant access for children with biliary atresia. ABSTRACT Introduction Biliary atresia (BA) is the most common indication for
Wallace MW +6 more
europepmc +2 more sources
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Current and emerging adjuvant therapies in biliary atresia
Frontiers in Pediatrics, 2022 Following Kasai hepatic portoenterostomy (HPE), most patients with biliary atresia will eventually require liver transplantation due to progressive cirrhosis and liver failure.
Scott C. Fligor +4 more
doaj +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Pediatrics In Review, 2006 Biliary atresia (BA) is a rare disease characterised by a biliary obstruction of unknown origin that presents in the neonatal period. It is the most frequent surgical cause of cholestatic jaundice in this age group. BA occurs in approximately 1/18,000 live births in Western Europe.
Garret S, Zallen +4 more
openaire +7 more sources
Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy
Hepatology, EarlyView., 2022 Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat +22 more
wiley +1 more source