Results 271 to 280 of about 9,207,506 (367)
Biliary cystic disease and neoplasia: surgical management
A Principe+7 more
openalex +1 more source
Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana+8 more
wiley +1 more source
Abstract This Phase 1 study of ubrogepant was conducted to establish the bioequivalence (BE) of the 50‐ and 100‐mg to‐be‐marketed (TBM) tablet formulations with the clinical trial (CT) 100‐mg tablet formulation and evaluate the food effect on the bioavailability of the 100‐mg TBM tablet. This 2‐part study enrolled healthy participants aged 18‐45 years.
Ramesh Boinpally, Joel M. Trugman
wiley +1 more source
Primary Cilia, Hypoxia, and Liver Dysfunction: A New Perspective on Biliary Atresia. [PDF]
Quelhas P, Morgado D, Santos JD.
europepmc +1 more source
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen+5 more
wiley +1 more source
Global burden of gallbladder and biliary diseases (1990-2021) with healthcare workforce analysis and projections to 2035. [PDF]
Dai F, Cai Y, Yang S, Zhang J, Dai Y.
europepmc +1 more source
Statin pharmacogenetic implementation guidelines are derived from evidence of primarily Eurocentrically biased study populations. Functional SLCO1B1 variants that are rare in these study populations have not been equitably investigated and are thus missing from guidelines.
Tanushree Haldar+11 more
wiley +1 more source
Left hepatic abscess with diaphragm involvement in the setting of biliary ostomy. [PDF]
Gershner GH, Hunter CJ, Bonds M.
europepmc +1 more source