Results 1 to 10 of about 159,964 (350)

Biliary tract cancer

European Journal of Surgical Oncology
Biliary tract cancers comprise a heterogeneous collection of malignancies usually described as cholangiocarcinoma of the intra- or extrahepatic bile duct, including perihilar cholangiocarcinoma and gallbladder cancer.A review of pertinent parts of the ESSO core curriculum for the UEMS diploma targets (Fellowships exam, EBSQ), based on updated and ...
Søreide, Kjetil, Dopazo, Cristina, Berrevoet, Frederik, Carrion-Alvarez, Lucia, Diaz-Nieto, Rafael, Andersson, Bodil, Stättner, Stefan, On behalf of the joint ESSO-EAHPBA-UEMS core curriculum working group, [missing]   +7 more
semanticscholar   +10 more sources

Immunotherapy in biliary tract cancer: reshaping the tumour microenvironment and advancing precision combination strategies [PDF]

Frontiers in Immunology
Biliary tract cancer, which includes intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gallbladder cancer, presents a significant clinical challenge because of its aggressive nature and limited therapeutic options.
Jingnan Xue, Longhao Zhang, Kai Zhang, Kai Zhou, Haitao Zhao   +4 more
doaj   +2 more sources

Microbiome and Biliary Tract Cancer

The Korean Journal of Gastroenterology
Biliary tract cancers encompass a group of malignancies that affect the bile ducts and gallbladder and are associated with a poor prognosis, often due to late diagnosis and limited treatment options.
Jin-Seok Park
doaj   +3 more sources

Establishment and characterization of an immortalized epithelial cell line from human gallbladder

Frontiers in Oncology, 2022
BackgroundAlthough a plethora of studies have employed multiple gallbladder cancer (GBC) cell lines, it is surprisingly noted that there is still lack of a normal gallbladder epithelial cell line as a normal counterpart, thus impeding substantially the ...
Ziyi Wang, Ziyi Wang, Ziyi Wang, Ziyi Wang, Shijia Wang, Shijia Wang, Shijia Wang, Shijia Wang, Ziheng Jia, Ziheng Jia, Ziheng Jia, Ziheng Jia, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Mao Yang, Mao Yang, Mao Yang, Mao Yang, Weikang Yan, Weikang Yan, Weikang Yan, Weikang Yan, Tao Chen, Tao Chen, Tao Chen, Tao Chen, Dongxi Xiang, Dongxi Xiang, Dongxi Xiang, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Yingbin Liu, Yingbin Liu, Yingbin Liu, Yingbin Liu   +39 more
doaj   +1 more source

lncRNA RP11-147L13.8 suppresses metastasis and chemo-resistance by modulating the phosphorylation of c-Jun protein in GBC

Molecular Therapy: Oncolytics, 2021
Long non-coding RNAs (lncRNAs) have been identified as critical contributors in tumor progression for many types of cancer. However, their functions in gallbladder cancer (GBC) have not been systematically clarified.
Bohao Zheng, Jiwen Wang, Kun Fan, Wentao Sun, Wenze Wan, Zhihui Gao, Xiaojian Ni, Dexiang Zhang, Xiaoling Ni, Tao Suo, Han Liu, Houbao Liu, Sheng Shen   +12 more
doaj   +1 more source

KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H ₂S axis and contributes to pancreatic cancer growth

Acta Biochimica et Biophysica Sinica, 2022
In pancreatic cancer, KRAS G12D can trigger pancreatic cancer initiation and development. Rapid tumor growth is often accompanied by excess intracellular reactive oxygen species (ROS) production, which is unfavorable to tumor.
Fan Kun, Zhang Shulong, Ni Xiaojian, Shen Sheng, Wang Jiwen, Sun Wentao, Suo Tao, Liu Han, Ni Xiaoling, Liu Houbao   +9 more
doaj   +1 more source

ARID1A Downregulation Predicts High PD-L1 Expression and Worse Clinical Outcome in Patients With Gallbladder Cancer

Frontiers in Oncology, 2022
BackgroundRecent studies have confirmed that AT-rich interactive domain-containing protein 1A (ARID1A) plays a critical role in tumorigenesis, but its role in gallbladder cancer (GBC) remains unclear.MethodsIn total, 224 patients from Zhongshan Hospital ...
Lingxi Nan, Lingxi Nan, Lingxi Nan, Changcheng Wang, Changcheng Wang, Changcheng Wang, Jie Wang, Shulong Zhang, Shulong Zhang, Shulong Zhang, Xiaobo Bo, Xiaobo Bo, Xiaobo Bo, Yueqi Wang, Yueqi Wang, Houbao Liu, Houbao Liu, Houbao Liu, Houbao Liu   +18 more
doaj   +1 more source

Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells.

PLoS ONE, 2023
Biliary tract cancer is a deadly disease with limited therapeutic options. Ouabain is a well-known inhibitor of the pumping function of Na+/K+-ATPase, though there is evidence that low concentrations of ouabain lead to a reduction of cell viability of ...
Christian Mayr, Tobias Kiesslich, Dino Bekric, Marlena Beyreis, Michael Kittl, Celina Ablinger, Elen Neureiter, Martin Pichler, Felix Prinz, Markus Ritter, Daniel Neureiter, Martin Jakab, Heidemarie Dobias   +12 more
doaj   +2 more sources

Cystic Duct Carcinoma: A New Classification System and the Clinicopathological Features of 62 Patients

Frontiers in Oncology, 2021
BackgroundCystic duct carcinoma (CDC) is a rare biliary malignancy with a low incidence and poor prognosis. However, the clinical landscape of the disease has not been clarified and no widely applicable classification system has been developed ...
Lingxi Nan, Lingxi Nan, Lingxi Nan, Changcheng Wang, Changcheng Wang, Changcheng Wang, Yajie Dai, Yajie Dai, Yajie Dai, Jie Wang, Jie Wang, Jie Wang, Xiaobo Bo, Xiaobo Bo, Xiaobo Bo, Shulong Zhang, Shulong Zhang, Dexiang Zhang, Dexiang Zhang, Houbao Liu, Houbao Liu, Houbao Liu, Houbao Liu, Yueqi Wang, Yueqi Wang, Yueqi Wang, Yueqi Wang   +26 more
doaj   +1 more source

An Overview of Epigenetic Methylation in Pancreatic Cancer Progression

Frontiers in Oncology, 2022
Over the past decades, the aberrant epigenetic modification, apart from genetic alteration, has emerged as dispensable events mediating the transformation of pancreatic cancer (PC).
Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Mao Yang, Mao Yang, Mao Yang, Shijia Wang, Shijia Wang, Shijia Wang, Sk Jahir Abbas, Sk Jahir Abbas, Junzhe Zhang, Junzhe Zhang, Junzhe Zhang, Yongsheng Li, Yongsheng Li, Yongsheng Li, Rong Shao, Yingbin Liu, Yingbin Liu, Yingbin Liu   +20 more
doaj   +1 more source