Results 1 to 10 of about 193,970 (395)

Robotic Surgery for Biliary Tract Cancer [PDF]

Cancers, 2022
Simple Summary Complete surgical resection of biliary tract cancer provides the best chance at long-term survival. These surgeries are complex and can be associated with high morbidity and prolonged recovery. Minimally invasive approaches have been shown
Lyonell B. Kone, Philip Bystrom, Ajay V. Maker   +2 more
openalex   +2 more sources

Randomized phase III study of gemcitabine, cisplatin plus S‐1 versus gemcitabine, cisplatin for advanced biliary tract cancer (KHBO1401‐ MITSUBA) [PDF]

Journal of hepato-biliary-pancreatic sciences, 2022
Gemcitabine/cisplatin (GC) combination therapy has been the standard palliative chemotherapy for patients with advanced biliary tract cancer (BTC). No randomized clinical trials have been able to demonstrate the survival benefit over GC during the past ...
Tatsuya Ioka, Masashi Kanai, Shogo Kobayashi, Daisuke Sakai, Hidetoshi Eguchi, Hideo Baba, Satoru Seo, Akinobu Taketomi, Tadatoshi Takayama, Hiroki Yamaue, Masahiro Takahashi, Masayuki Sho, Keiko Kamei, Jiro Fujimoto, Masanori Toyoda, Junzo Shimizu, Takuma Goto, Yoshitaro Shindo, Kenichi Yoshimura, Etsuro Hatano, Hiroaki Nagano   +20 more
openalex   +2 more sources

Global, regional, and national burden and trends analysis of gallbladder and biliary tract cancer from 1990 to 2019 and predictions to 2030: a systematic analysis for the Global Burden of Disease Study 2019

Frontiers in Medicine
ObjectivesOur aim was to explore the disease burden caused by gallbladder and biliary tract cancer globally, regionally, and nationally, by age and sex.MethodsThe absolute number of cases and age-standardized rates (ASR) of incidence, prevalence ...
Jiao Su, Yuanhao Liang, Xiaofeng He
doaj   +2 more sources

Dysbiosis of the Fecal and Biliary Microbiota in Biliary Tract Cancer [PDF]

Cancers, 2021
Characteristic bile duct and gut microbiota have been identified in patients with chronic biliary tract disease. This study aimed to characterize the fecal and bile microbiota in biliary tract cancer (BTC) patients and their relationship. Patients with BTC (n = 30) and benign biliary disease (BBD) without cholangitis (n = 11) were included. Ten healthy,
Zensho Ito, Shigeo Koido, Kumiko Kato, Toshitaka Odamaki, Sankichi Horiuchi, Takafumi Akasu, Masayuki Saruta, Taigo Hata, Yu Kumagai, Shuichi Fujioka, Takeyuki Misawa, Jin-zhong Xiao, Nobuhiro Sato, Toshifumi Ohkusa   +13 more
openaire   +3 more sources

Microbiome and Biliary Tract Cancer

The Korean Journal of Gastroenterology
Biliary tract cancers encompass a group of malignancies that affect the bile ducts and gallbladder and are associated with a poor prognosis, often due to late diagnosis and limited treatment options.
Jin-Seok Park
doaj   +3 more sources

Causal relationship between immune cell phenotypes and risk of biliary tract cancer: evidence from Mendelian randomization analysis

Frontiers in Immunology
BackgroundBiliary tract cancer stands as a prevalent illness, posing significant risks to human health, where immune cells are pivotal in both its development and recovery processes.
YaLan Hu, Kui Wang, Kui Wang, Yuhua Chen, Yongli Jin, Qiang Guo, Hui Tang   +6 more
doaj   +2 more sources

Immunotherapy in biliary tract cancer: reshaping the tumour microenvironment and advancing precision combination strategies [PDF]

Frontiers in Immunology
Biliary tract cancer, which includes intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gallbladder cancer, presents a significant clinical challenge because of its aggressive nature and limited therapeutic options.
Jingnan Xue, Longhao Zhang, Kai Zhang, Kai Zhou, Haitao Zhao   +4 more
doaj   +2 more sources

Establishment and characterization of an immortalized epithelial cell line from human gallbladder

Frontiers in Oncology, 2022
BackgroundAlthough a plethora of studies have employed multiple gallbladder cancer (GBC) cell lines, it is surprisingly noted that there is still lack of a normal gallbladder epithelial cell line as a normal counterpart, thus impeding substantially the ...
Ziyi Wang, Ziyi Wang, Ziyi Wang, Ziyi Wang, Shijia Wang, Shijia Wang, Shijia Wang, Shijia Wang, Ziheng Jia, Ziheng Jia, Ziheng Jia, Ziheng Jia, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Mao Yang, Mao Yang, Mao Yang, Mao Yang, Weikang Yan, Weikang Yan, Weikang Yan, Weikang Yan, Tao Chen, Tao Chen, Tao Chen, Tao Chen, Dongxi Xiang, Dongxi Xiang, Dongxi Xiang, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Yingbin Liu, Yingbin Liu, Yingbin Liu, Yingbin Liu   +39 more
doaj   +1 more source

lncRNA RP11-147L13.8 suppresses metastasis and chemo-resistance by modulating the phosphorylation of c-Jun protein in GBC

Molecular Therapy: Oncolytics, 2021
Long non-coding RNAs (lncRNAs) have been identified as critical contributors in tumor progression for many types of cancer. However, their functions in gallbladder cancer (GBC) have not been systematically clarified.
Bohao Zheng, Jiwen Wang, Kun Fan, Wentao Sun, Wenze Wan, Zhihui Gao, Xiaojian Ni, Dexiang Zhang, Xiaoling Ni, Tao Suo, Han Liu, Houbao Liu, Sheng Shen   +12 more
doaj   +1 more source

KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H ₂S axis and contributes to pancreatic cancer growth

Acta Biochimica et Biophysica Sinica, 2022
In pancreatic cancer, KRAS G12D can trigger pancreatic cancer initiation and development. Rapid tumor growth is often accompanied by excess intracellular reactive oxygen species (ROS) production, which is unfavorable to tumor.
Fan Kun, Zhang Shulong, Ni Xiaojian, Shen Sheng, Wang Jiwen, Sun Wentao, Suo Tao, Liu Han, Ni Xiaoling, Liu Houbao   +9 more
doaj   +1 more source