Results 21 to 30 of about 3,474,042 (288)

Efficacy and safety of S-1 following gemcitabine with cisplatin for advanced biliary tract cancer [PDF]

, 2021
滋賀医科大学博士（医学）pdfBackground Combination therapy of gemcitabine with cisplatin (GC) is a standard first-line therapy for unresectable or recurrent biliary tract cancer (BTC).
井上, 博登, INOUE, Hiroto
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Chemotherapy for biliary tract cancer: real-world experience in a single institute [PDF]

, 2020
2020-11The standard chemotherapy regimen for unresectable or recurrent biliary tract cancer is gemcitabine combined with cisplatin (GC). To evaluate the effectiveness and safety of chemotherapy in patients with unresectable or recurrent biliary tract ...
Nagino, Masato, Shimokata, Tomoya, Mizuno, Takashi, Mitsuma, Ayako, Sugishita, Mihoko, Ando, Masahiko, Urakawa, Hiroshi, Ebata, Tomoki, Takano, Yuko, Inada-Inoue, Megumi, Matsuoka, Ayumu, Miyai, Yuki, Maeda, Osamu, Morita, Sachi, Ando, Yuichi   +14 more
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Clinical Advances in the Diagnosis and Treatment of Biliary Tract Diseases

, 2023
In recent years, there have been remarkable advances in the diagnosis and treatment of biliary tract diseases. Among them, the advanced endoscopic treatments and anti-tumor therapies for biliary tract cancer are outstanding.

core   +1 more source

Case report: A de novo ERBB3 mutation develops in a gallbladder cancer patient carrying BRCA1 mutation after effective treatment with olaparib

Frontiers in Oncology, 2023
BackgroundGallbladder cancer (GBC) is highly lethal and resistant to most chemotherapeutic drugs. GBC was reported to carry multiple genetic mutations such as TP53, K-RAS, and ERBB2/3.
Jing-Xiao Yang, Zi-Yao Jia, Fa-Tao Liu, Wen-Guang Wu, Xue-Chuan Li, Xue-Chuan Li, Xue-Chuan Li, Lu Zou, Lu Zou, Lu Zou, Huai-Feng Li, Huai-Feng Li, Huai-Feng Li, Fei Zhang, Fei Zhang, Fei Zhang, Run-Fa Bao, Run-Fa Bao, Run-Fa Bao, Shu-You Peng, Wan Yee Lau, Yun Liu, Mao-Lan Li, Ying-Bin Liu, Ying-Bin Liu, Ying-Bin Liu   +25 more
doaj   +1 more source

Exosomal MicroRNA signature acts as an efficient biomarker for non-invasive diagnosis of gallbladder carcinoma

iScience, 2022
Summary: Through a three-step study that relies on biomarker discovery, training, and validation, we identified a set of five exosomal microRNAs (miRNAs) that can be used to evaluate the risk of gallbladder carcinoma (GBC), including miR-552-3p, miR-581,
Pinghua Yang, Fengliang Song, Xinwei Yang, Xingzhou Yan, Xinyu Huang, Zhengjun Qiu, Zhijian Wen, Chi Liang, Xianglei Xin, Zhengqin Lei, Kecheng Zhang, Jue Yang, Hu Liu, Hongcheng Wang, Shijun Xiang, Liang Li, Baohua Zhang, Hongyang Wang   +17 more
doaj   +1 more source

Global, regional, and national burden of respiratory tracancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 [PDF]

, 2021
Background Prevention, control, and treatment of respiratory tract cancers are important steps towards achieving target 3.4 of the UN Sustainable Development Goals (SDGs)—a one-third reduction in premature mortality due to non-communicable diseases by ...
GBD 2019 Respiratory Tract Cancer Collaborators, Francesco S. Violante   +1 more
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Promising Genomic Testing for Biliary Tract Cancer Using Endoscopic Ultrasound-Guided Fine-Needle Aspiration/Biopsy Specimens

Diagnostics, 2022
The undesired prognosis of biliary tract cancer is mainly attributed to the difficult detection of cancer lesions, including intraepithelial neoplasia and no standard examination for screening.
Masaki Kuwatani, Kazumichi Kawakubo, Naoya Sakamoto   +2 more
doaj   +1 more source

Interplay between the Human Microbiome and Biliary Tract Cancer: Implications for Pathogenesis and Therapy

Microorganisms, 2023
Biliary tract cancer, encompassing intrahepatic and extrahepatic cholangiocarcinoma as well as gallbladder carcinoma, stands as a prevalent malignancy characterized by escalating incidence rates and unfavorable prognoses.
Cheng Ye, Chunlu Dong, Yanyan Lin, Huaqing Shi, Wence Zhou   +4 more
doaj   +1 more source

Gut Microbiota in Diagnosis, Therapy and Prognosis of Cholangiocarcinoma and Gallbladder Carcinoma—A Scoping Review

Microorganisms, 2023
Cancers of the biliary tract are more common in Asia than in Europe, but are highly lethal due to delayed diagnosis and aggressive tumor biology. Since the biliary tract is in direct contact with the gut via the enterohepatic circulation, this suggests a
Ann-Kathrin Lederer, Hannah Rasel, Eva Kohnert, Clemens Kreutz, Roman Huber, Mohamed Tarek Badr, Patricia K. E. Dellweg, Fabian Bartsch, Hauke Lang   +8 more
doaj   +1 more source

N6-methyladenosine modification promotes hepatocarcinogenesis through circ-CDYL-enriched and EpCAM-positive liver tumor-initiating exosomes

iScience, 2023
Summary: CircRNAs play multiple roles in a variety of cellular processes. We found that Circ-CDYL is highly enriched in early HCC plasma exosomes. Moreover, EpCAM+ HCC cells and exosomes had significant Circ-CDYL levels.
Yanping Wei, Jingbo Fu, Hailing Zhang, Yan Ling, Xuewu Tang, Shuowu Liu, Miao Yu, Fuyan Liu, Guokun Zhuang, Haihua Qian, Kecheng Zhang, Pinhua Yang, Xinwei Yang, Qi Yang, Shennian Ge, Baohua Zhang, Yexiong Tan, Liang Li, Hongyang Wang   +18 more
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