Results 161 to 170 of about 193,970 (395)

Renoprotective Effect of Coix lachryma‐jobi L. Seed Polysaccharides in Adenine‐Induced Chronic Renal Failure by Blocking Gut Urea Metabolism

Food Frontiers, EarlyView.
ABSTRACT Dietary soluble fiber may alleviate renal damage in chronic kidney disease (CKD) by promoting intestinal urea excretion, though the underlying mechanisms remain unclear. This study investigated the digestion, fermentation, and renoprotective effects of Coix lachryma‐jobi L.
Hongmei Yin, Wanjun Liao, Yilian Huang, Qiang Hong, Na Zhang, Xiaodan Shi, Zongcai Tu, Hui Wang, Zuohua Xie, Tao Yuan   +9 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment [PDF]

, 2017
A Rai, AG Tolcher, AX Zhu, Caio Max S Rocha-Lima, David Portnoy, DP Brooks, E Gabriela Chiorean, E Suzuki, J Albores-Saavedra, J Nelson, J Valle, JE Rogers, JF Guion-Dussere, Jitendra Gandhi, L Goyal, M Yanagisawa, Manik Amin, NV Rajeshkumar, NV Rajeshkumar, P Papakostas, R Pazdur, Richard Kim, RK Jain, RL Siegel, S He, SC Lee, SY Oh, T Sasaki, T Walter, Tao Song, William P Harris   +30 more
core   +3 more sources

Liver transplantation in biliary atresia with concomitant hepatoma. [PDF]

, 1972
Two cases are reported in which the very infrequently reported association was found of liver cell carcinoma and biliary cirrhosis secondary to congenital biliary atresia.
Giles, G, Halgrimson, CG, Lilly, J, Martineau, G, Starzl, TE, Van Wyk, J   +5 more
core  

Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer.

New England Journal of Medicine, 2010
J. Valle, H. Wasan, D. Palmer, D. Cunningham, A. Anthoney, A. Maraveyas, S. Madhusudan, T. Iveson, S. Hughes, S. Pereira, M. Roughton, J. Bridgewater   +11 more
semanticscholar   +1 more source

Hesperetin Mitigate Idiopathic Pulmonary Fibrosis by Regulating Gut Microbiota and Acetate and Butyrate Levels via the Gut‐Lung Axis

Food Frontiers, EarlyView.
Hesperetin inhibits bleomycin‐induced idiopathic pulmonary fibrosis by regulating gut microbiota and acetate and butyrate levels via the gut‐lung axis. ABSTRACT In the post‐epidemic and aging era, idiopathic pulmonary fibrosis (IPF) has become one of the major diseases endangering human health.
Xia Meng, Zeren Cheng, Xianpu Huang, Mengqi Fu, Ling Shen, Kejing Tang, Shuxun Liu, Mingfei Yao, Qing Gu, Ping Li   +9 more
wiley   +1 more source

Trends in Receipt of Adjuvant Chemotherapy and its Impact on Survival in Resected Biliary Tract Cancers [PDF]

, 2023
Kristen E. Rhodin, Annie Liu, Alex J. Bartholomew, Ryan J. Kramer, Anika Parameswaran, Hope E. Uronis, John H. Strickler, David S. Hsu, Michael A. Morse, Kevin N. Shah, Garth S. Herbert, Sabino Zani, Daniel P. Nussbaum, Peter J. Allen, Michael E. Lidsky   +14 more
openalex   +1 more source

The Clinical Landscape of Cell-Free DNA Alterations in 1,671 Patients with Advanced Biliary Tract Cancer.

Annals of Oncology, 2022
Jacob E. Berchuck, F. Facchinetti, D. Ditoro, I. Baiev, U. Majeed, Stephanie Reyes, Christopher T. Chen, Karen Zhang, R. Sharman, Pedro Luiz Serrano Usón Junior, J. Maurer, R. Shroff, C. Pritchard, Meng-Ju Wu, D. Catenacci, M. Javle, L. Friboulet, A. Hollebecque, N. Bardeesy, A. Zhu, J. Lennerz, Benjamin Tan, M. Borad, A. Parikh, L. Kiedrowski, R. Kelley, K. Mody, D. Juric, L. Goyal   +28 more
semanticscholar   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Supplementary Table S3 from Devimistat in Combination with Gemcitabine and Cisplatin in Biliary Tract Cancer: Preclinical Evaluation and Phase Ib Multicenter Clinical Trial (BilT-04)

, 2023
Arathi Mohan, Kent A. Griffith, Fulei Wuchu, David B. Zhen, Chandan Kumar‐Sinha, Oxana Crysler, David Hsiehchen, Thomas Enzler, Dominique Dippman, Valerie Gunchick, Abhinav Achreja, Olamide Animasahun, Srinadh Choppara, Minal Nenwani, Arul M. Chinnaiyan, Deepak Nagrath, Mark M. Zalupski, Vaibhav Sahai   +17 more
openalex   +1 more source