Results 11 to 20 of about 193,970 (395)

Biliary tract cancer

open access: yesEuropean Journal of Surgical Oncology
Biliary tract cancers comprise a heterogeneous collection of malignancies usually described as cholangiocarcinoma of the intra- or extrahepatic bile duct, including perihilar cholangiocarcinoma and gallbladder cancer.A review of pertinent parts of the ESSO core curriculum for the UEMS diploma targets (Fellowships exam, EBSQ), based on updated and ...
Søreide, Kjetil   +7 more
  +10 more sources

ARID1A Downregulation Predicts High PD-L1 Expression and Worse Clinical Outcome in Patients With Gallbladder Cancer

open access: yesFrontiers in Oncology, 2022
BackgroundRecent studies have confirmed that AT-rich interactive domain-containing protein 1A (ARID1A) plays a critical role in tumorigenesis, but its role in gallbladder cancer (GBC) remains unclear.MethodsIn total, 224 patients from Zhongshan Hospital ...
Lingxi Nan   +18 more
doaj   +1 more source

Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells.

open access: yesPLoS ONE, 2023
Biliary tract cancer is a deadly disease with limited therapeutic options. Ouabain is a well-known inhibitor of the pumping function of Na+/K+-ATPase, though there is evidence that low concentrations of ouabain lead to a reduction of cell viability of ...
Christian Mayr   +12 more
doaj   +2 more sources

Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer: An early exploratory analysis of real‐world data

open access: yesLiver international (Print), 2023
The TOPAZ‐1 phase III trial reported a survival benefit with the anti‐programmed death cell ligand 1 (anti‐PD‐L1) durvalumab in combination with gemcitabine and cisplatin in patients with advanced biliary tract cancer.
M. Rimini   +39 more
semanticscholar   +1 more source

Tucatinib and Trastuzumab for Previously Treated Human Epidermal Growth Factor Receptor 2–Positive Metastatic Biliary Tract Cancer (SGNTUC-019): A Phase II Basket Study

open access: yesJournal of Clinical Oncology, 2023
PURPOSE To evaluate the efficacy and safety of tucatinib and trastuzumab in patients with previously treated human epidermal growth factor receptor 2–positive (HER2+) metastatic biliary tract cancer (mBTC).
Y. Nakamura   +27 more
semanticscholar   +1 more source

Cystic Duct Carcinoma: A New Classification System and the Clinicopathological Features of 62 Patients

open access: yesFrontiers in Oncology, 2021
BackgroundCystic duct carcinoma (CDC) is a rare biliary malignancy with a low incidence and poor prognosis. However, the clinical landscape of the disease has not been clarified and no widely applicable classification system has been developed ...
Lingxi Nan   +26 more
doaj   +1 more source

Updates in Biliary Tract Cancers

open access: yesCancers, 2022
Biliary tract cancers (BTCs) are a heterogeneous group of malignancies arising from the epithelium of the biliary tree [...]
Daneng Li   +3 more
openaire   +2 more sources

An Overview of Epigenetic Methylation in Pancreatic Cancer Progression

open access: yesFrontiers in Oncology, 2022
Over the past decades, the aberrant epigenetic modification, apart from genetic alteration, has emerged as dispensable events mediating the transformation of pancreatic cancer (PC).
Yuhao Zhao   +20 more
doaj   +1 more source

Development and Validation of a Prognostic Nomogram Based on the Systemic Immune-Inflammation Index for Resectable Gallbladder Cancer to Predict Survival and Chemotherapy Benefit

open access: yesFrontiers in Oncology, 2021
ObjectivesTo investigate the prognostic significance of the systemic immune-inflammation index (SII) in patients after radical cholecystectomy for gallbladder cancer (GBC) using overall survival (OS) as the primary outcome measure.MethodsBased on data ...
Lin Li   +48 more
doaj   +1 more source

Immunotherapy change overcomes acquired resistance after chemo-immunotherapy in unresectable biliary tract cancer. [PDF]

open access: goldCancer Immunol Immunother
Chen X   +16 more
europepmc   +3 more sources

Home - About - Disclaimer - Privacy