Results 61 to 70 of about 193,970 (395)

The footprint of gut microbiota in gallbladder cancer: a mechanistic review

Frontiers in Cellular and Infection Microbiology
Gallbladder cancer (GBC) is the most common malignant tumor of the biliary system with the worst prognosis. Even after radical surgery, the majority of patients with GBC have difficulty achieving a clinical cure. The risk of tumor recurrence remains more
Shujie Liu, Weijian Li, Weijian Li, Weijian Li, Weijian Li, Jun Chen, Jun Chen, Jun Chen, Jun Chen, Maolan Li, Maolan Li, Maolan Li, Maolan Li, Yajun Geng, Yajun Geng, Yajun Geng, Yajun Geng, Yingbin Liu, Yingbin Liu, Yingbin Liu, Yingbin Liu, Wenguang Wu, Wenguang Wu, Wenguang Wu, Wenguang Wu   +24 more
doaj   +1 more source

Promoter hypermethylation of SHOX2 and SEPT9 is a potential biomarker for minimally invasive diagnosis in adenocarcinomas of the biliary tract [PDF]

, 2016
Clinicopathological data of the 20 biliary tract cancer cases and 100 gender- and age-matched controls included in plasma study.
A. Kania, A. Semaan, D. Dietrich, G. Kristiansen, H. Matthaei, J. C. Kalff, N. Schäfer, P. Lingohr, P. Schaefer, V. Branchi   +9 more
core   +2 more sources

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

Camrelizumab plus gemcitabine and oxaliplatin (GEMOX) in patients with advanced biliary tract cancer: a single-arm, open-label, phase II trial

Journal for ImmunoTherapy of Cancer, 2020
Background Immune checkpoint inhibitors monotherapy has been studied in patients with advanced biliary tract cancer (BTC). The aim of this study was to assess the efficacy and safety of camrelizumab, plus gemcitabine and oxaliplatin (GEMOX) as first-line
Xiaofeng Chen, Xiaofeng Wu, Hao Wu, Yanhong Gu, Y. Shao, Q. Shao, Feipeng Zhu, Xiao Li, X. Qian, Jun Hu, Fengjiao Zhao, Weidong Mao, Jing Sun, Jian Wang, Gaohua Han, Changxian Li, Yongxiang Xia, P. Seesaha, Dongqin Zhu, Huajun Li, Junling Zhang, Guoqiang Wang, Xuehao Wang, Xiangcheng Li, Y. Shu   +24 more
semanticscholar   +1 more source

Cancer Risk in Patients With Systemic Sclerosis: A Nationwide Cohort Study in South Korea 2004 to 2021

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na, Su Jin Choi, Sojeong Park, Minae Park, Doo‐Ho Lim   +4 more
wiley   +1 more source

Low expression of RACK1 is associated with metastasis and worse prognosis in cholangiocarcinoma

Heliyon
Background: Cholangiocarcinoma is a poorly prognostic malignant tumor, and the metastatic stage of cancer is not an early stage when diagnosed. Lymph node metastasis is common in the early stage.
Zhihui Gao, Wentao Sun, Xiaojian Ni, Wenze Wan, Tao Suo, Xiaoling Ni, Han Liu, Na Li, Sheng Shen, Houbao Liu   +9 more
doaj   +1 more source

Liver resections: complications and survival outcome [PDF]

, 2007
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

MicroRNA markers for the diagnosis of pancreatic and biliary-tract cancers.

PLoS ONE, 2015
It is difficult to detect pancreatic cancer or biliary-tract cancer at an early stage using current diagnostic technology. Utilizing microRNA (miRNA) markers that are stably present in peripheral blood, we aimed to identify pancreatic and biliary-tract ...
Motohiro Kojima, Hiroko Sudo, Junpei Kawauchi, Satoko Takizawa, Satoshi Kondou, Hitoshi Nobumasa, Atsushi Ochiai   +6 more
doaj   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source