Results 51 to 60 of about 3,737,366 (186)

Genomic mutation characteristics and prognosis of biliary tract cancer

, 2022
      59 formalin fixed paraffin-embedded (FFPE) tissues were obtained from patients with operable biliary tract cancer. We conducted targeted capture sequencing of 620 genes through high-throughput sequencing technology and analyzed the fusion ...
Guo (12674386)
core   +1 more source

MicroRNA markers for the diagnosis of pancreatic and biliary-tract cancers.

PLoS ONE, 2015
It is difficult to detect pancreatic cancer or biliary-tract cancer at an early stage using current diagnostic technology. Utilizing microRNA (miRNA) markers that are stably present in peripheral blood, we aimed to identify pancreatic and biliary-tract ...
Motohiro Kojima, Hiroko Sudo, Junpei Kawauchi, Satoko Takizawa, Satoshi Kondou, Hitoshi Nobumasa, Atsushi Ochiai   +6 more
doaj   +1 more source

Biliary tract cancer patient-derived xenografts: Surgeon impact on individualized medicine

JHEP Reports, 2020
Background & Aims: Biliary tract tumors are uncommon but highly aggressive malignancies with poor survival outcomes. Due to their low incidence, research into effective therapeutics has been limited.
Jennifer L. Leiting, Stephen J. Murphy, John R. Bergquist, Matthew C. Hernandez, Tommy Ivanics, Amro M. Abdelrahman, Lin Yang, Isaac Lynch, James B. Smadbeck, Sean P. Cleary, David M. Nagorney, Michael S. Torbenson, Rondell P. Graham, Lewis R. Roberts, Gregory J. Gores, Rory L. Smoot, Mark J. Truty   +16 more
doaj   +1 more source

Mutational signatures in 175 Chinese gastric cancer patients

BMC Cancer
Background Gastric cancer (GC), a molecularly heterogeneous disease, is the third leading cause of cancer death worldwide. The majority of GC cases worldwide occur in East Asia, predominantly China.
Fatao Liu, Nan Hu, Kewei Jiang, Huaitian Liu, Mingyi Wang, Ying Hu, Tongwu Zhang, Ho-Hsiang Wu, Howard Yang, Hao Weng, Ping Dong, Carol Giffen, Bin Zhu, Maxwell P. Lee, Christian C. Abnet, Philip R. Taylor, Yun Liu, Yingbin Liu, Alisa M. Goldstein   +18 more
doaj   +1 more source

Occurrence of pancreatic, biliary tract, and gallbladder cancers in Alaska Native people, 1973–2007 [PDF]

International Journal of Circumpolar Health, 2012
Objectives: To describe the occurrence of pancreatic, biliary tract, and gallbladder cancers within the Alaska Native (AN) population. Study design: Population-based analysis utilizing a tumor registry and comparative population data.
Steven R. Alberts, Janet J. Kelly, Ramkumar Ashokkumar, Anne P. Lanier   +3 more
doaj   +1 more source

An RNA–RNA crosstalk network involving HMGB1 and RICTOR facilitates hepatocellular carcinoma tumorigenesis by promoting glutamine metabolism and impedes immunotherapy by PD-L1+ exosomes activity

Signal Transduction and Targeted Therapy, 2021
Hepatocellular carcinoma (HCC) is the global leading cause of cancer-related deaths due to the deficiency of targets for precision therapy. A new modality of epigenetic regulation has emerged involving RNA–RNA crosstalk networks where two or more ...
Yanping Wei, Xuewu Tang, Yibin Ren, Yun Yang, Fengliang Song, Jingbo Fu, Shuowu Liu, Miao Yu, Jing Chen, Suyang Wang, Kecheng Zhang, Yexiong Tan, Zhipeng Han, Lixin Wei, Baohua Zhang, Zhangjun Cheng, Liang Li, Hongyang Wang   +17 more
doaj   +1 more source

Supplementary Figure S2 from Devimistat in Combination with Gemcitabine and Cisplatin in Biliary Tract Cancer: Preclinical Evaluation and Phase Ib Multicenter Clinical Trial (BilT-04)

, 2023
Mutational Landscape of Biliary Tract Cancer Cell ...
Srinadh Choppara (15561376), David Hsiehchen (15561361), Deepak Nagrath (15561385), David B. Zhen (15561355), Dominique Dippman (15561367), Kent A. Griffith (15561349), Oxana Crysler (15561358), Abhinav Achreja (15561370), Arathi Mohan (15561346), Valerie Gunchick (15560621), Mark M. Zalupski (15561388), Olamide Animasahun (15561373), Arul M. Chinnaiyan (15561382), Vaibhav Sahai (15560624), Minal Nenwani (15561379), Thomas Enzler (15561364), Chandan Kumar-Sinha (15130650), Fulei Wuchu (15561352)   +17 more
core   +2 more sources

Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers

Nature Communications, 2023
In biliary tract cancer HER2 alterations correlate with poor prognosis. Here, the authors present the results of a phase II clinical trial reporting the efficacy and safety of the tyrosine kinase inhibitor neratinib in patients with HER2-mutation ...
James J. Harding, Sarina A. Piha-Paul, Ronak H. Shah, Jessica J. Murphy, James M. Cleary, Geoffrey I. Shapiro, David I. Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M. Ford, Mónica Arnedos, Salomon M. Stemmer, Christelle de la Fouchardiere, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S. Duygu Selcuklu, Michael F. Berger, Lisa D. Eli, Funda Meric-Bernstam, Komal Jhaveri, David B. Solit, Ghassan K. Abou-Alfa   +27 more
doaj   +1 more source

Ultrasound Assessment of Diffuse and Focal Gallbladder Wall Pathology and Risk Stratification

Инновационная медицина Кубани
Background: Accurate statistics on mortality from biliary tract cancer in Russia are unavailable. Biliary tract cancer is characterized by an extremely unfavorable prognosis, with a 5-year survival rate of approximately 2%.
A. N. Katrich, R. N. Oksuzyan
doaj   +1 more source

Diet and biliary tract cancer risk in Shanghai, China.

PLoS ONE, 2017
Trends in biliary tract cancer incidence rates have increased in Shanghai, China. These trends have coincided with economic and developmental growth, as well as a shift in dietary patterns to a more Westernized diet.
Shakira M Nelson, Yu-Tang Gao, Leticia M Nogueira, Ming-Chang Shen, Bingsheng Wang, Asif Rashid, Ann W Hsing, Jill Koshiol   +7 more
doaj   +1 more source