Results 91 to 100 of about 36,750 (293)

Durvalumab plus gemcitabine-cisplatin versus S-1 plus gemcitabine-cisplatin in advanced biliary tract cancer: a comparative study

ESMO Gastrointestinal Oncology
Background and purpose: Following the TOPAZ-1 trial, chemoimmunotherapy with durvalumab plus gemcitabine and cisplatin (GCD) became the standard first-line treatment of advanced biliary tract cancer (BTC).
T. Satake, M. Sasaki, H. Imaoka, S. Taro, K. Inoue, T. Taira, G. Igarashi, M. Amisaki, H. Takahashi, S. Mitsunaga, M. Ikeda   +10 more
doaj   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

FOLFIRI as second-line treatment of metastatic biliary tract cancer patients

Autopsy and Case Reports, 2019
The combination of cisplatin and gemcitabine is the standard first-line treatment of metastatic biliary tract cancer (BTC) patients. The benefit of second-line chemotherapy in these patients is controversial.
Rafael Caparica, Adrien Lengelé, Winnie Bekolo, Alain Hendlisz   +3 more
doaj  

Vacancy defect‐induced electron homing breaks phosphodiester bonds for RNA depletion‐driven cancer therapy

BMEMat, EarlyView.
Illustration of 5% S‐vacancy Bi2S3 mediated phosphodiester bonds cleavage in RNA of hepatocellular carcinoma cells, which suppressing ERI3 expression, inhibiting cell proliferation and promoting apoptosis. Abstract Genome‐wide hypertranscription is a hallmark of malignant progression.
Chuncheng Yang, Zehao Shen, Guangming Xiang, Zhe Liu, Huaxin Liu, Jiabei Li, Ao Wang, Yelin Wu, Peiran Zhao, Xingwu Jiang, Jinghan Wang, Xiaoqing Jiang, Wenbo Bu   +12 more
wiley   +1 more source

Health Benefits of Polysaccharides in Red Algae: A Comprehensive Review

Food Frontiers, EarlyView.
Graphical abstract showing the health benefits of red algal polysaccharides. ABSTRACT Humans have long consumed red algae (especially by the Asian community), and their polysaccharide extracts (carrageenan, agar) are extensively used in the food industry as gel thickeners.
Sammueal Jun Kai Ong, Matthew Myint, Sean Chia, Chee Fan Tan, Yi Fan Hong, Meiyappan Lakshmanan, Ying Swan Ho, Thomas T. Wheeler, Xuezhi Bi, Ian Walsh, Kuin Tian Pang   +10 more
wiley   +1 more source

Magnetic Resonance Imaging versus Computed Tomography for Biliary Tract Intraductal Papillary Mucinous Neoplasm (BT-IPMN): A Diagnostic Performance Analysis

, 2020
Jing Li, Yuanlin Yu, Lulong Zhu, Yuping Li, Qing He   +4 more
openalex   +2 more sources

ANTEGRADE ENDOBILIARY INTERVENTIONS IN PATIENTS WITH UNRESECTABLE BILIARY TRACT MALIGNANT NEOPLASMS COMPLICATED BY JAUNDICE

, 2022
V. V. Boyko, Yu. V. Avdosyev, D. О. Yevtushenko, A. L. Sochneva, I. A. Taraban, Р. M. Smachilo, D. V. Minukhin, О. М. Шевченко   +7 more
openalex   +2 more sources

[Internal biliary diversions in inoperable neoplasms of the biliary tract and pancreas].

Il Giornale di chirurgia, 1991
The authors report their experience with the treatment of mechanical jaundice in inoperable malignant neoplasms of the bile ducts and pancreas. They emphasize the importance of intrahepatic peripheral biliodigestive derivations (Soupault and Couinaud operation).
G, Giordano, T, Losacco, G, Garofalo, F, Grimaldi, G, Petracca, N, Mustacchio, D, Novelli, G, Cannone, G, Carbonara   +8 more
openaire   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Clinical and pathological features of intraductal papillary neoplasm of the biliary tract and gallbladder [PDF]

, 2015
Sean Bennett, Esmeralda Celia Marginean, Melanie Paquin‐Gobeil, Jason K. Wasserman, Joel Weaver, Richard Mimeault, Fady Balaa, Guillaume Martel   +7 more
openalex   +1 more source