Results 191 to 200 of about 595,039 (309)

A Randomized Phase II Study of Combination Atezolizumab and Varlilumab (CDX-1127) with or without Cobimetinib in Previously Treated Unresectable Biliary Tract Cancer. [PDF]

Clin Cancer Res
Heumann TR, Lu J, Wang H, Phelps M, Zhu Q, Anders R, Mitchell S, Leatherman J, Abbott N, Kim K, Imhof T, Xie Z, Partey A, Li D, Kunk PR, Iyer RV, Dayyani F, Kankeu Fonkoua L, Kalyan A, Gbolahan OB, Javle MM, Davis SL, Florou V, Spencer K, Sharon E, Yarchoan M, Lesinski GB, Azad NS.   +27 more
europepmc   +1 more source

Medication Use and Risk of Microscopic Colitis: A Propensity‐Matched Analysis of US Adults ≥ 50 Years (2014–2024)

Alimentary Pharmacology &Therapeutics, EarlyView.
Commonly prescribed NSAIDs, PPIs and SSRIs were associated with a higher risk of microscopic colitis after propensity score matching, whereas ACE inhibitors, ARBs and statins showed no significant association. ABSTRACT Background The association between medications—including non‐steroidal anti‐inflammatory drugs (NSAIDs), proton pump inhibitors (PPIs ...
Yassine Kilani, Farah Heis, Andrew Dugaesescu, Youssef Hafez, Shadi Hamdeh, Wissam Kiwan, Mahmoud Y. Madi   +6 more
wiley   +1 more source

Gallbladder malignancy in the setting of Mirizzi syndrome with bile duct involvement: a case report. [PDF]

J Surg Case Rep
Poluyanoff AA, Ajadi EA, Flood D, Salzberg AD.   +3 more
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

Phase II Trial of Nivolumab in Advanced Solid Tumors Based on Genomic Profiling: BELIEVE Trial (NCCH1901) Subcohort

Cancer Science, EarlyView.
Off‐label nivolumab treatment guided by CGP results was evaluated in 56 patients with advanced solid tumors. TMB‐High was the predominant biomarker leading to nivolumab treatment. Nivolumab showed limited clinical benefit in 50 patients with measurable disease, with an ORR of 16.0%, DCR of 40.0%, median PFS of 2.7 months, and median OS of 7.2 months ...
Masashi Kanai, Kuniko Sunami, Tatsunori Shimoi, Satoshi Nishiwaki, Ichiro Kinoshita, Tetsuhiro Yoshinami, Chigusa Morizane, Yusuke Sato, Toshio Kubo, Mamoru Ito, Hiroshi Nishihara, Toru Mukohara, Hidekazu Shirota, Ryo Ko, Taro Shibata, Manabu Muto, Noboru Yamamoto   +16 more
wiley   +1 more source

Risk Factors for Peritonitis Associated With Endoscopic Ultrasound-guided Hepaticogastrostomy. [PDF]

DEN Open
Sato J, Ishiwatari H, Sakamoto H, Doi T, Yamamura M, Takada K, Yoshida M, Ito S, Kawata N, Imai K, Hotta K, Ono H.   +11 more
europepmc   +1 more source

Genomic Evolution and Immune Contexture With Therapeutic Relevance in Pancreatic Neuroendocrine Neoplasms

Cancer Science, EarlyView.
Lineage‐dependent immunogenomic landscapes and biologically informed therapy in pancreatic neuroendocrine neoplasms. Pancreatic neuroendocrine neoplasms display lineage‐dependent immunogenomic landscapes, in which genomic alterations, epigenetic states, antigen‐presentation status, immune‐cell infiltration, and suppressive microenvironments co‐evolve ...
Yohei Tabe, Eito Nakagawa, Daisuke Asano, Eriko Katsuta, Daisuke Ban, Shogo Kumagai   +5 more
wiley   +1 more source

Remnant Cystic Duct Carcinoma Mimicking Duodenal Carcinoma after Cholecystectomy: A Case Report. [PDF]

Surg Case Rep
Okura T, Aoki H, Obayashi H, Oka E, Futagami H, Sato M, Ogawa T, Hori N, Katsuda K, Tanakaya K.   +9 more
europepmc   +1 more source

Mucinous Cystic Neoplasms of the Liver and Extrahepatic Biliary Tract [PDF]

, 2018
Dzeina Mezale, Ilze Strumfa, Andrejs Vanags, Guntis Bahs, Boriss Strumfs, Arturs Silovs, Reinis Riekstins, Janis Gardovskis   +7 more
openaire   +1 more source