Results 1 to 10 of about 299,762 (246)

Reactive Oxygen Species (ROS) and Antioxidants as Immunomodulators in Exercise: Implications for Heme Oxygenase and Bilirubin

open access: yesAntioxidants, 2022
Exercise is commonly prescribed as a lifestyle treatment for chronic metabolic diseases as it functions as an insulin sensitizer, cardio-protectant, and essential lifestyle tool for effective weight maintenance. Exercise boosts the production of reactive
David Travis Thomas   +4 more
doaj   +2 more sources

Bilirubin Protects Transplanted Islets by Targeting Ferroptosis

open access: yesFrontiers in Pharmacology, 2020
Islet transplantation is an attractive treatment for type 1 diabetic patients. However, transplanted islets suffered from considerable cell death due to inflammatory reactions and oxidative stress.
Qing Yao   +5 more
doaj   +2 more sources

Bilirubin Metabolism [PDF]

open access: greenMolecular Aspects of Medicine, 1963
Barbara H. Billing
openalex   +3 more sources

A component could not be larger than the whole, polyclonal immunoglobulin interference in conjugated/direct bilirubin assay and elimination: A case report

open access: yesClinical Case Reports, 2022
Analytical interferences (hemolysis, icterus, paraproteinemia, and lipemia) are of great concern in laboratory tests. In our case report, the conjugated bilirubin result of a patient was significantly higher than the total bilirubin.
Neda Soleimani   +2 more
doaj   +1 more source

Loss of Biliverdin Reductase Increases Oxidative Stress in the Cyanobacterium Synechococcus sp. PCC 7002

open access: yesMicroorganisms, 2023
Oxygenic photosynthesis requires metal-rich cofactors and electron-transfer components that can produce reactive oxygen species (ROS) that are highly toxic to cyanobacterial cells. Biliverdin reductase (BvdR) reduces biliverdin IXα to bilirubin, which is
Wendy M. Schluchter   +6 more
doaj   +1 more source

Bilirubin ameliorates murine atherosclerosis through inhibiting cholesterol synthesis and reshaping the immune system

open access: yesJournal of Translational Medicine, 2022
Atherosclerosis is a chronic inflammatory disease caused mainly by lipid accumulation and excessive inflammatory immune response. Although the lipid-lowering and cardioprotective properties of bilirubin, as well as the negative relationship between ...
Guanmei Wen   +4 more
semanticscholar   +1 more source

Inhibition of Lipid Accumulation in Skeletal Muscle and Liver Cells: A Protective Mechanism of Bilirubin Against Diabetes Mellitus Type 2

open access: yesFrontiers in Pharmacology, 2021
Ectopic lipid accumulation in skeletal muscle and liver drives the pathogenesis of diabetes mellitus type 2 (DMT2). Mild hyperbilirubinaemia has been repeatedly suggested to play a role in the prevention of DMT2 and is known for its capacity to shape an ...
Claudia A. Hana   +18 more
doaj   +1 more source

Measurement and clinical usefulness of bilirubin in liver disease

open access: yesAdvances in laboratory medicine, 2021
Elevated plasma bilirubin levels are a frequent clinical finding. It can be secondary to alterations in any stage of its metabolism: (a) excess bilirubin production (i.e., pathologic hemolysis); (b) impaired liver uptake, with elevation of indirect ...
A. G. Guerra Ruíz   +7 more
semanticscholar   +1 more source

Direct Bilirubin Levels Predict Long-Term Outcomes in Patients With Acute Coronary Syndrome Under Different Glucose Metabolism Status: A 6.5-Year Cohort Study of Three-Vessel Disease

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: There is controversy over the relationship between bilirubin and coronary artery disease. This study aimed to evaluate the predictive value of direct bilirubin (DB) in patients with complex acute coronary syndrome (ACS).Methods: From April ...
Yue Liu   +12 more
doaj   +1 more source

Serum Bilirubin and Bilirubin/Albumin Ratio as Predictors of Bilirubin Encephalopathy [PDF]

open access: yesPediatrics, 2014
BACKGROUND AND OBJECTIVE:Bilirubin/albumin ratio (B/A) may provide a better estimate of free bilirubin than total serum bilirubin (TSB), thus improving identification of newborns at risk for bilirubin encephalopathy. The objective of the study was to identify thresholds and compare specificities of TSB and B/A in detecting patients with acute and ...
Hazem S. Abou-Youssef   +8 more
openaire   +3 more sources

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