Results 131 to 140 of about 258,858 (308)

Cord Blood Alkaline Phosphatase Level as a Predictor for Neonatal Jaundice in Healthy Term Newborns [PDF]

open access: yesJournal of Pediatrics Review
Background: Neonatal hyperbilirubinemia is one of the common and benign conditions occurring in 80% of preterm and 60% of term neonates during their first week of life.
Vishnu Priyaa Rajasegaran   +2 more
doaj  

The Protective Effect of Bilirubin on MAFLD May Be Mediated by Improving Insulin Re-Sistance and Alleviating Chronic Inflammation [PDF]

open access: yes
Mengying Yang,1,* Jing Liu,1,* Xiaoman Liu,1 Qianqian Li,1 Jun Liu,2 Baogui Wang1 1Department of Infectious Disease, Fuyang People’s Hospital, Fuyang, Anhui, People’s Republic of China; 2Physical Examination Center, Fuyang People’s Hospital ...
Liu X, Liu J, Wang B, Yang M, Li Q
core  

Studies on urinary bilirubin Part 1. The excretion of bilirubin into urine from the toad's kidney [PDF]

open access: yes, 1975
In order to elucidate which is the major functional unit, tubulus or glomerulus, on bilirubin excretion into urine, toad (Rana Clamitans) was used for the experiment because the distribution of blood vessels in toads was anatomically well separated to ...
Yamamoto, Takehiko
core  

Hepatic morphology and serum biochemical profile according to dry and rainy seasons in Pygocentrus nattereri (Characiformes: Serrasalmidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract This study investigated the physiological and morphological adaptations of the liver of the carnivorous fish Pygocentrus nattereri (piranha) in response to seasonal variations (dry and rainy seasons) in the Brazilian Pantanal. The objective was to describe how the liver, a central organ in metabolic regulation, responds to environmental ...
Maria Eduarda Corona Garcia   +9 more
wiley   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Increased Risk of Intrahepatic Cholestasis of Pregnancy in Women With Systemic Lupus Erythematosus Exposed to Azathioprine

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the risk of intrahepatic cholestasis of pregnancy (ICP) in azathioprine (AZA)–exposed versus unexposed systemic lupus erythematosus (SLE) pregnancies within the multicenter prospective Lupus in Pregnancy (LEGACY) cohort. Methods LEGACY is conducted at Systemic Lupus International Collaborating Clinics in Canada, South Korea, Peru,
Reem Farhat   +14 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Bilirubin metabolism [PDF]

open access: yesMolecular Aspects of Medicine, 1963
openaire   +2 more sources

The Effect of Conjugated Bilirubin on the Measurement of Unbound Bilirubin

open access: yesActa Paediatrica
ABSTRACT Aim Unbound bilirubin (Bf) is a stronger predictor of neurotoxicity in newborns than that of total serum bilirubin (TSB). Standard Bf assays rely on peroxidase methods (e.g., Arrows analyser), whereas UBCheck employs a near‐infrared fluorescence sensor.
Kleinfeld, Alan   +3 more
openaire   +2 more sources

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner   +52 more
wiley   +1 more source

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