The choroid plexus in health and in disease: dialogues into and out of the brain [PDF]
, 2017 This article brings the choroid plexus into the context of health and disease. It is remarkable that the choroid plexus, composed by a monolayer of epithelial cells that lie in a highly vascularized stroma, floating within the brain ventricles, gets so ...
Brito, Maria Alexandra +6 more
core +1 more source
Localization of bilirubin in phospholipid bilayers by parallax analysis of fluorescence quenching1
Journal of Lipid Research, 2001 It has been proposed that the neurotoxicity observed in severely jaundiced infants results from the binding of unconjugated bilirubin to nerve cell membranes.
Stephen D. Zucker +3 more
doaj +1 more source
Defects in bile pigment metabolism causing jaundice [PDF]
, 1961 The excretion of bilirubin and therefore the relief of jaundice is dependent upon at least three factors. First, the bilirubin must be conjugated and thus converted into a water soluble compound: this means its conversion to an ester glucuronide although
Billing, Barbara H.
core +1 more source
The cytotoxic effect of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells is modulated by the expression level of MRP1 but not MDR1 [PDF]
, 2008 In vitro and in vivo studies have demonstrated that UCB (unconjugated bilirubin) is neurotoxic. Although previous studies suggested that both MRP1 (multidrug resistance-associated protein 1) and MDR1 (multidrug resistance protein 1) may protect cells ...
Aranda, A +5 more
core +4 more sources
A case of intraplacental twin transfusion [PDF]
, 1967 There have been several reports of polycythaemia in one of uniovular twins with anaemia in the other twin. This syndrome has been recently fully recorded and reviewed by Corney and Aherne (1965).
Vassallo Agius, Paul
core
Learning lessons from adverse drug reactions in children [PDF]
, 2016 Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults.
Bodenstein +7 more
core +2 more sources
Severe Neonatal Hyperbilirubinemia; Causes and Contributing Factors Leading to Exchange Transfusion at Ghaem Hospital in Mashhad [PDF]
Acta Medica Iranica, 2010 "nHyperbilirubinemia is common in neonates; it can have a serious rising course. Due to its critical morbidity called "kernicterus", severe neonatal hyperbilirubinemia causes which lead to exchange transfusion, should be clarified.
Farhad Heydarian, Mina Majdi
doaj +2 more sources
Risk Factors for Kernicterus in Neonatal Jaundice
Gomal Journal of Medical Sciences, 2010 Background: Kernicterus is a neurologic syndrome resulting from deposition of unconjugated bilirubin in the basal ganglia and brain stem nuclei. The aim of this study was to identify the risk factors for kernicterus in neonatal jaundice.
Hussain Bux Korejo +5 more
doaj
Ampicillin/Sulbactam-induced Hemolytic Anemia Manifested as Hyperbilirubinemia in a Preterm Infant [PDF]
, 2016 A female was born at 36+5 weeks of gestation with a birth weight of 2,120 g. Apgar score was 7 at 1 minute and 9 at 5 minutes. Shortly after birth, tachypnea, chest retraction, and a severe build-up of oral secretions were noted.
���������
core +2 more sources
پزشکی بالینی ابن سینا, 2016 Introduction & Objective: Jaundice is a common problem in infants in the first days after birth. Jaundice due to serious complications such as kernicterus requires special attention.
Zeynab Mahmodi, Fatemeh Mahmodi
doaj