Results 21 to 30 of about 7,236 (206)

Genetic Association of UGT1A1 Promoter Variants (c.-3279T>G and c.-3156G>A) with Neonatal Hyperbili-rubinemia in an Iranian Population [PDF]

Iranian Journal of Neonatology, 2021
Background: Several studies have reported that two promoter variants (c.-3279T>G and c.-3156G>A) in UDP-glucuronosyltransferase (UGT1A1) gene may contribute to neonatal hyperbilirubinemia.
Nasim Pouralizadeh, Gholamali Mamouri, Abbas Boskabadi, Hassan Boskabadi, Houshang Rafatpanah, Ali Moradi, Hassan Mehrad-Majd   +6 more
doaj   +1 more source

Brainstem auditory evoked responses in an equine patient population. Part II: foals. [PDF]

, 2014
BackgroundReports of the use of brainstem auditory evoked response (BAER) as a diagnostic modality in foals have been limited.Hypothesis/objectivesTo describe BAER findings and associated causes of hearing loss in foals.AnimalsStudy group 18 foals (15 ...
Aleman, M, Holliday, TA, Madigan, JE, Williams, DC   +3 more
core   +1 more source

MGE-Like Neural Progenitor Cell Survival and Expression of Parvalbumin and Proenkephalin in a Jaundiced Rat Model of Kernicterus

Cell Transplantation, 2022
Kernicterus is a permanent condition caused by brain damage from bilirubin toxicity. Dystonia is one of the most debilitating symptoms of kernicterus and results from damage to the globus pallidus (GP).
Fu-Chen Yang, Jay L. Vivian, Catherine Traxler, Steven M. Shapiro, John A. Stanford   +4 more
doaj   +1 more source

Demystifying non-invasive approaches for screening jaundice in low resource settings: a review

Frontiers in Pediatrics, 2023
All national and international pediatric guidelines universally prescribe meticulous bilirubin screening for neonates as a critical measure to mitigate the incidence of acute bilirubin encephalopathy (ABE) and Kernicterus.
Umme Abiha, Umme Abiha, Dip Sankar Banerjee, Saptarshi Mandal   +3 more
doaj   +1 more source

The Causes and Risk Factors in Patients with Kernicterus Referred to the Clinic of Pediatric Neurology during the Years 2011 to 2016

مجله دانشکده پزشکی اصفهان, 2018
Background: Neonatal jaundice has potentially severe side effects such as kernicterus. Prevention of kernicterus and hyperbilirubinemia is based on finding neonates with risk factors and starting treatment as soon as possible. Therefore, this study aimed
Jafar Nasiri, Mohammadreza Ghazavi, Mohammadali Pourmirzaei, Abdorahim Pak   +3 more
doaj   +1 more source

Bilirubin-Induced Neurological Damage: Current and Emerging iPSC-Derived Brain Organoid Models

Cells, 2022
Bilirubin-induced neurological damage (BIND) has been a subject of studies for decades, yet the molecular mechanisms at the core of this damage remain largely unknown.
Abida Islam Pranty, Sara Shumka, James Adjaye   +2 more
doaj   +1 more source

Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis [PDF]

, 2018
Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the ...
Anderson, Dg, Barkhuizen, M, Ferraldeschi, M, Gavilanes, Awd., Kramer, Bw, REGISTRY Investigators of the European Huntington's Disease, Network, Ristori, G, Rodrigues, Fb, Romano, S, Wild, Ej, Winkens, B   +10 more
core   +1 more source

Newborn Metabolic Profile Associated with Hyperbilirubinemia With and Without Kernicterus

Clinical and Translational Science, 2019
Our objective was to assess the relationship between hyperbilirubinemia with and without kernicterus and metabolic profile at newborn screening. Included were 1,693,658 infants divided into a training or testing subset in a ratio of 3:1.
Molly E. McCarthy, Scott P. Oltman, Rebecca J. Baer, Kelli K. Ryckman, Elizabeth E. Rogers, Martina A. Steurer‐Muller, John S. Witte, Laura L. Jelliffe‐Pawlowski   +7 more
doaj   +1 more source

MRI in Kernicterus

Pediatric Neurology Briefs, 1995
The magnetic resonance images (MRI) of three children with athetotic cerebral palsy and severe neonatal jaundice were examined in the Department of Pediatric Neurology, Ohzora-no-iye Hospital and Seirei-Mikatahara General Hospital, Shizuoka, Japan.
J Gordon Millichap
doaj   +1 more source

DIAGNOSIS AND MANAGEMENT OF HYPERIBILIRUBINEMIA IN THE NEONATE [PDF]

Romanian Journal of Pediatrics, 2008
Bilirubin-induced neurologic dysfunction can occur in term and near-term healty babies. The term babies who are unwell, the preterm neonates, and the infants who have multiple comorbidities constitute a group vulnerable to bilirubin neurotxicity.
Valeriu Popescu, Daniela Patrichi
doaj   +1 more source