Results 11 to 20 of about 7,236 (206)

Kernicterus Continues to Occur in the USA Despite Concerted Preventive Efforts [PDF]

open access: yesCase Reports in Pediatrics
Kernicterus spectrum disorder continues to occur in the USA, even after improvements in detecting and managing hyperbilirubinemia were brought about by the 2022 AAP revised guidelines. Three of eight new cases of kernicterus occurring in our state during
Bailey B. Zeiler   +3 more
doaj   +3 more sources

Effects of Repetitive Transcranial Magnetic Stimulation on Pallidum GABAergic Neurons and Motor Function in Rat Models of Kernicterus [PDF]

open access: yesBrain Sciences, 2023
Kernicterus is a serious complication of hyperbilirubinemia, caused by neuronal injury due to excessive unconjugated bilirubin (UCB) in specific brain areas.
Nanqin Wang   +5 more
doaj   +2 more sources

Clinicopathological Spectrum of Bilirubin Encephalopathy/Kernicterus

open access: yesDiagnostics, 2019
Bilirubin encephalopathy/kernicterus is relatively rare, but continues to occur despite universal newborn screening. What is more interesting is the spectrum of clinical and even neuropathological findings that have been reported in the literature to be ...
Sumit Das, Frank van Landeghem
exaly   +3 more sources

The Importance of Neuroimaging Follow-Up in Bilirubin-Induced Encephalopathy: A Clinical Case Review [PDF]

open access: yesBrain Sciences
Introduction: Hyperbilirubinemia in newborns can lead to kernicterus, a severe form of neonatal encephalopathy caused by bilirubin toxicity. Despite timely interventions such as exchange transfusion, kernicterus can still develop, especially in high-risk
Martina Resaz   +5 more
doaj   +2 more sources

Developmental outcome of severe neonatal indirect hyperbilirubinemia [PDF]

open access: yesJournal of Research in Clinical Medicine, 2021
Background: Indirect hyperbilirubinemia is one of the most common causes of hospitalization in the neonatal period and its potential association with brain damage is well established.
Manizheh Mostafa Gharehbaghi   +3 more
doaj   +1 more source

Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome

open access: yesCells, 2023
Bilirubin-induced neurological damage (BIND), which might progress to kernicterus, occurs as a consequence of defects in the bilirubin conjugation machinery, thus enabling albumin-unbound free bilirubin (BF) to cross the blood–brain barrier and ...
Abida Islam Pranty   +2 more
doaj   +1 more source

MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017

open access: yesRadiology Case Reports, 2018
Characteristic magnetic resonance imaging (MRI) findings in patients with chronic kernicterus are bilateral and symmetric T2-weighted hyperintensities in the globus pallidus.
Getachew Assefa Neknek, MD   +3 more
doaj   +1 more source

Dystonia Scales for Children: Challenges and Obstacles in DBS Practice. [PDF]

open access: yesMov Disord Clin Pract
Abstract Background Dystonia in pediatric patients often coexists with other movement disorders and neurodevelopmental issues. Current rating scales for evaluating pediatric deep brain stimulation (DBS) candidates are not universally applicable and often require a non‐validated combination of the existing scales.
Montiel M   +4 more
europepmc   +2 more sources

Bilirubin-Induced Transcriptomic Imprinting in Neonatal Hyperbilirubinemia

open access: yesBiology, 2023
Recent findings indicated aberrant epigenetic control of the central nervous system (CNS) development in hyperbilirubinemic Gunn rats as an additional cause of cerebellar hypoplasia, the landmark of bilirubin neurotoxicity in rodents.
John Paul Llido   +7 more
doaj   +1 more source

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