Results 151 to 160 of about 242,163 (312)

The Effect of Conjugated Bilirubin on the Measurement of Unbound Bilirubin

open access: yesActa Paediatrica
ABSTRACT Aim Unbound bilirubin (Bf) is a stronger predictor of neurotoxicity in newborns than that of total serum bilirubin (TSB). Standard Bf assays rely on peroxidase methods (e.g., Arrows analyser), whereas UBCheck employs a near‐infrared fluorescence sensor.
Kleinfeld, Alan   +3 more
openaire   +2 more sources

Population pharmacokinetic/pharmacodynamic modelling to evaluate favipiravir in combination with lopinavir–ritonavir in patients with COVID‐19

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman   +9 more
wiley   +1 more source

Does Bilirubin Have a Causal Relationship With Vitiligo? A Mendelian Randomization Study and Bioinformatics Analysis

open access: yes
Danfeng Xu,1 Yinmeng Yin,2 Yan Teng,1 Youming Huang,1 Yong Yu,1 Xiaohua Tao,1 Yibin Fan,1 Xiaoxia Ding1 1Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital ...
Yin Y   +7 more
core  

Serum Bilirubin and Genes Controlling Bilirubin Concentrations as Biomarkers for Cardiovascular Disease

open access: yes, 2010
BACKGROUNDSerum bilirubin has been consistently shown to be inversely related to cardiovascular disease (CVD). Recent studies showed serum bilirubin to be associated with CVD-related factors such as diabetes, metabolic syndrome, and body mass index ...
Harvey A Schwertner   +2 more
core   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh   +5 more
wiley   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong   +13 more
wiley   +1 more source

Perbandingan Kadar Bilirubin Direk Menggunakan Sampel Serum Dan Plasma

open access: yes, 2011
viii, 32 hlm; ilus: 27 ...
Dian Nur Indah Sari
core  

Biliary bilirubin excretion in Wistar Kyoto rat under loading of bilirubin [PDF]

open access: yes, 1993
The mechanism of biliary bilirubin excretion in Wistar Kyoto rats was studied. Bilirubin diglucuronide is a main fraction of biliary bilirubin in Wistar Kyoto rats, and is similar to that of humans but differs from that of control (SD and Wistar) rats ...
Kawasaki, Norihiko, 川崎, 紀彦
core  

Bilirubin determination in gallstones

open access: yes, 1991
The determination of bilirubin in gallstones is carried out by means of several methods, but most frequently by spectrophotometric determination of azobilirubin.
Djurdjic, V.   +2 more
core   +1 more source

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

open access: yes
American Journal of Hematology, EarlyView.
Ferras Alashkar   +10 more
wiley   +1 more source

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