Primary hepatic cancer (PHC), especially hepatocellular carcinoma (HCC), is still a significant burden worldwide. The efficacy of diagnosis, treatment response monitoring, and prognostication using laboratory biomarkers is still a challenge. This study analyzed multi‐laboratory parameters pre‐ and post‐treatment and their associations with clinical and
Xiaowei Chi +3 more
wiley +1 more source
Development of a Physiologically Based Model of Bilirubin Metabolism in Health and Disease and Its Comparison With Real-World Data. [PDF]
Sayin AZ, Kuepfer L.
europepmc +1 more source
Reframing Post‐Hepatectomy Liver Failure as a Determinant of Post‐Recurrence Survival in HCC
ABSTRACT Background Post‐hepatectomy liver failure (PHLF) is traditionally considered a transient perioperative complication with limited long‐term consequences, yet its long‐term oncologic implications in hepatocellular carcinoma (HCC) remain unclear. Methods Patients undergoing primary hepatectomy for HCC between 2007 and 2018 were analyzed.
Hiroshi Horie +7 more
wiley +1 more source
Reduction of serum bilirubin levels after endoscopic biliary drainage in patients with extrahepatic biliary obstruction and its significance. [PDF]
Naidu KSC +11 more
europepmc +1 more source
ABSTRACT Background/Purpose Although type 1 autoimmune pancreatitis (AIP) responds well to corticosteroids, spontaneous remission can also occur. This study evaluated long‐term outcomes and predictors of delayed steroid initiation in AIP patients initially managed conservatively.
Yasuhiro Kuraishi +9 more
wiley +1 more source
Endoscopic ultrasound-guided gallbladder drainage for bilirubin normalization in distal malignant biliary obstruction: A focused review. [PDF]
Martino A +13 more
europepmc +1 more source
Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He +11 more
wiley +1 more source
Exploratory longitudinal cohort study of modest bilirubin-driven biochemical liver alterations after SARS-CoV-2 infection in a selected subgroup of patients with Wilson's disease and liver cirrhosis. [PDF]
Köhrer S +7 more
europepmc +1 more source

