Results 21 to 30 of about 299,762 (246)

Induction of BVR-A Expression by Korean Red Ginseng in Murine Hippocampal Astrocytes: Role of Bilirubin in Mitochondrial Function via the LKB1–SIRT1–ERRα Axis

Antioxidants, 2022
The beneficial effects of Korean red ginseng extract (KRGE) on the central nervous system (CNS) have been reported. Among the CNS cells, astrocytes possess robust antioxidative properties and regenerative potential.
Sunhong Moon, Chang-Hee Kim, Jinhong Park, Minsu Kim, Hui Su Jeon, Young-Myeong Kim, Yoon Kyung Choi   +6 more
doaj   +1 more source

CRIGLER- NAJJAR SYNDROME – CASE REPORT

Slovenska pediatrija, 2022
Crigler-Najjar syndrome is a rare genetic disorder that causes severe unconjugated hyperbilirubinaemia. The syndrome is caused by a mutation in the UGT1A1 gene, which results in a deficiency or complete lack of the UGT1A1 enzyme, which is responsible for
Anja Šelih, Manca Velkavrh
doaj   +1 more source

The jaundiced newborn: which early monitoring for a safe discharge?

La Pediatria Medica e Chirurgica, 2013
Neonatal jaundice is one of the most common causes of prolonged hospital stay or readmission of a near-term or term baby. Reason of concern at early discharge of a jaundiced newborn is that of bilirubin neurotoxicity, even if a serum bilirubin ...
S. Pratesi, C. Dani
doaj   +1 more source

Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis.

Nature Materials, 2019
While conventional approaches for inflammatory bowel diseases mainly focus on suppressing hyperactive immune responses, it remains unclear how to address disrupted intestinal barriers, dysbiosis of the gut commensal microbiota and dysregulated mucosal ...
Yonghyun Lee, Kohei Sugihara, Merritt G. Gillilland, S. Jon, N. Kamada, J. Moon   +5 more
semanticscholar   +1 more source

On detecting reference level of acrolein content in children's blood

Analiz Riska Zdorovʹû, 2017
The article gives the results of complex chemical-analytical and clinical-laboratory research in course of which biological media of children living in Perm region were examined.
T.S. Ulanova, O.O. Sinitsyna, T.D. Karnazhitskaya, E.O. Zavernenkova   +3 more
doaj   +1 more source

Genetic variations underlying Gilbert syndrome and HBV infection outcomes: a cross-sectional study

Frontiers in Genetics, 2023
Background: Constant cellular damage causes a poor prognosis of hepatitis B virus (HBV) infection. Accumulating evidence indicates the cytoprotective properties of bilirubin.
Bilian Yao, Qi Xu, Xinxin Zhang, Xinxin Zhang, Xinxin Zhang, Yue Han, Yue Han   +6 more
doaj   +1 more source

Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator–activated receptor α

Journal of Biological Chemistry, 2020
Activation of lipid-burning pathways in the fat-storing white adipose tissue (WAT) is a promising strategy to improve metabolic health and reduce obesity, insulin resistance, and type II diabetes.
Darren M. Gordon, Kari L. Neifer, Abdul-rizaq Hamoud, Charles F Hawk, A. Nestor-Kalinoski, Scott A Miruzzi, Michael P. Morran, S. Adeosun, J. Sarver, P. Erhardt, R. Mccullumsmith, D. Stec, T. Hinds   +12 more
semanticscholar   +1 more source

Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate

Frontiers in Pharmacology, 2020
The inverse relationship of plasma bilirubin levels with liver fat accumulation has prompted the possibility of bilirubin as a therapeutic for non-alcoholic fatty liver disease. Here, we used diet-induced obese mice with non-alcoholic fatty liver disease
T. Hinds, J. Creeden, Darren M. Gordon, D. Stec, M. Donald, D. Stec   +5 more
semanticscholar   +1 more source

Some blood biochemical indices of mice with pttg gene knockout

Біологічні студії, 2011
Liver injury of any etiology is accompanied by increased fibrogenesis. One of the key genes that may influence in the development of liver fibrosis, is pttg gene (Pituitary tumor transforming gene).
O. P. Kanyuka, Ye. Z. Filyak, S. V. Afanasyev, N. O. Sybirna   +3 more
doaj   +1 more source

The Association of COVID-19 Degree on Transamination and Bilirubin Levels of COVID-19 Patients in RSUD Dr. Saiful Anwar Malang

Clinical and Research Journal in Internal Medicine, 2022
Background : Corona virus 2019 (COVID-19) is an infectious viral disease caused by SARS-CoV-2 that has infected the world. COVID-19 can cause abnormalities which are characterized by increased levels of the enzyme transaminase and bilirubin.
Ade Rahmawati, Syifa Mustika
doaj   +1 more source