Results 21 to 30 of about 396,943 (392)

Identification of Binding Regions of Bilirubin in the Ligand-Binding Pocket of the Peroxisome Proliferator-Activated Receptor-A (PPARalpha)

open access: yesMolecules, 2021
Recent work has shown that bilirubin has a hormonal function by binding to the peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor that drives the transcription of genes to control adiposity.
Darren M. Gordon   +3 more
semanticscholar   +1 more source

Bilirubin as a Metabolic Hormone: The Physiological Relevance of Low Levels.

open access: yesAmerican Journal of Physiology. Endocrinology and Metabolism, 2020
Recent research on bilirubin, a historically well-known waste product of heme catabolism, suggests an entirely new function as a metabolic hormone that drives gene transcription by nuclear receptors.
J. Creeden   +3 more
semanticscholar   +1 more source

Bilirubin oxidase from myrothecium verrucaria physically absorbed on graphite electrodes. Insights into the alternative resting from and the sources of activity loss [PDF]

open access: yes, 2015
The oxygen reduction reaction is one of the most important chemical processes in energy converting systems and living organisms. Mediator-less, direct electro-catalytic reduction of oxygen to water was achieved on spectrographite electrodes modified by
Carmen Castro   +4 more
core   +6 more sources

Molecular Physiology and Pathophysiology of Bilirubin Handling by the Blood, Liver, Intestine, and Brain in the Newborn.

open access: yesPhysiological Reviews, 2020
Bilirubin is the end product of heme catabolism formed during a process that involves oxidation-reduction reactions and conserves iron body stores. Unconjugated hyperbilirubinemia is common in newborn infants, but rare later in life. The basic physiology
T. Hansen, R. Wong, D. Stevenson
semanticscholar   +1 more source

Ursodeoxycholic acid improves bilirubin but not albumin in primary biliary cirrhosis: further evidence for nonefficacy. [PDF]

open access: yes, 2013
BACKGROUND/AIM: In randomised controlled trials (RCTs) of ursodeoxycholic acid (UDCA), although serum bilirubin is frequently reduced, its effect on disease progression and mortality is unclear.
Burroughs, Andrew K   +5 more
core   +3 more sources

External Drainage of Giant Infantile Choledochal Cyst before Definitive Repair: Is it Worth? [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Infantile Choledochal Cysts (IFCC) usually present with jaundice, acholic stool and abdominal lump or abdominal distension. If the surgical intervention is delayed, they rapidly progress to liver fibrosis which is considered to be irreversible if ...
Vijai Datta Upadhyaya   +3 more
doaj   +1 more source

Studies on Bile Pigments II. Seperation of Natural Direct Bilirubins [PDF]

open access: yes, 1956
Separation of both forms of the direct bilirubin were carried out from the dog's gallbladder bile, and further isolations of them were also done. 1. The natural salt-form bilirubin was isolated after separation on the column of aluminium oxide with a n ...
Sakamoto, Takeshi
core   +1 more source

β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor

open access: yesFrontiers in Immunology, 2018
Background & aimsKnowledge about innate antimicrobial defense of the liver is limited. We investigated hepatic expression and regulation of antimicrobial peptides with focus on the human beta defensin-1 (hBD-1).MethodsRadial diffusion assay was used ...
Thomas Klag   +14 more
doaj   +1 more source

An institutional-based observational study of the effect of iodinated contrast media used in computed tomography scan on liver function tests in a tertiary care hospital

open access: yesAsian Journal of Medical Sciences, 2022
Background: Iodine-based contrast media are used to obtain contrast-enhanced computed tomography (CECT) images for better visualization of anatomical structures and improved diagnostic accuracy.
Keshab Mukhopadhyay   +3 more
doaj   +1 more source

Association between neonatal jaundice and autism spectrum disorders among children: a meta-analysis [PDF]

open access: yesClinical and Experimental Pediatrics, 2020
Autism spectrum disorder is a common neurodevelopmental disorder with an unknown etiology. The correlation between neonatal jaundice and the risk of developing autism spectrum disorder was investigated previously.
Ensiyeh Jenabi   +2 more
doaj   +1 more source

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