Results 51 to 60 of about 258,858 (308)

Dynamic Change of Albumin-Bilirubin Score Is Good Predictive Parameter for Prognosis in Chronic Hepatitis C-hepatocellular Carcinoma Patients Receiving Transarterial Chemoembolization

Diagnostics, 2022
Background and Aims: The Albumin-Bilirubin (ALBI) grade is a good index for liver function evaluation and is also associated with the outcomes of hepatocellular carcinoma patients receiving TACE. However, the correlation between the dynamic change to the
Po-Ting Lin, Wei Teng, Wen-Juei Jeng, Wei-Ting Chen, Yi-Chung Hsieh, Chien-Hao Huang, Kar-Wai Lui, Chen-Fu Hung, Ching-Ting Wang, Pei-Mei Chai, Chen-Chun Lin, Chun-Yen Lin, Shi-Ming Lin, I-Shyan Sheen   +13 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Some blood biochemical indices of mice with pttg gene knockout

Біологічні студії, 2011
Liver injury of any etiology is accompanied by increased fibrogenesis. One of the key genes that may influence in the development of liver fibrosis, is pttg gene (Pituitary tumor transforming gene).
O. P. Kanyuka, Ye. Z. Filyak, S. V. Afanasyev, N. O. Sybirna   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Spectrophotometry for cerebrospinal fluid pigment analysis [PDF]

, 2006
The use of spectrophotometry for the analysis of the cerebrospinal fluid (CSF) is reviewed. The clinically relevant CSF pigments--oxyhemoglobin and bilirubin--are introduced and discussed with regard to clinical differential diagnosis and potentially ...
Sharpe, L.T., Petzold, A., Keir, G.
core  

Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study

, 2015
© 2014 Surgical Associates Ltd. Appendicitis is a common clinical diagnosis aided by biochemical, haematological and radiological investigations.
Chambers, A C, Davies, H., Patil, A V, Bismohun, S. L., Patil, A. V., Chambers, A. C., Davies, H, White, P., White, Paul, Bismohun, S L, White, P   +10 more
core   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Investigation of the Frequency, Causes and Consequences of Cholestasis in Infants Referred to AmirKola Children\'s Hospital During the Years 2012-2022 [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Children with cholestasis experience a wide spectrum of disease, ranging from transient liver function abnormalities to life-threatening conditions.
Zahra Ghanbari tilami, Sanaz Mehrabani, Mohammadreza Esmaeili Dooki, Maryam Nikpour, Yadollah Zahedpasha, Mousa Ahmadpour, Abbas Hadipour   +6 more
doaj  

Regulation of haem oxygenase-1 nitrosative stress in cardiac cells. [PDF]

, 2005
The reactive nitrogen species (RNS) nitric oxide (NO), nitroxyl anion (NO") and nitrosonium cation (NO+), modulate a myriad of biological processes. The microsomal haem oxygenases (HO-1, HO-2 and HO-3) oxidatively catabolise haem to bilirubin, carbon ...
Naughton, P.
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