Results 71 to 80 of about 242,163 (312)

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Liver enzymes in diabetic and non diabetic subjects with clinically diagnosed hepatitis

IMC Journal of Medical Science, 2011
The occurrence of liver disease and raised liver enzymes is common in diabetic patients and the increasing level of enzymes indicates the severity of hepatic injury.
Bidhan Chandra Sarkar, Hasi Rani Saha, Palash Kumar Sarker, Niranjan Kumar Sana, M Abu Sayeed, Subhagata Choudhury   +5 more
doaj  

Serum Bilirubin Is Correlated With the Progression of IgA Vasculitis With Nephritis

Frontiers in Medicine, 2021
Background: Bilirubin has been identified as an endogenous antioxidant and cellular protectant. The present study was performed to clarify the potential influence of serum bilirubin on IgA vasculitis with nephritis (IgAV-N).Methods: One hundred and ...
Jiaxing Tan, Jiaxing Tan, Gaiqin Pei, Gaiqin Pei, Yicong Xu, Tengyue Hu, Li Tan, Li Tan, Zhengxia Zhong, Zhengxia Zhong, Padamata Tarun, Yi Tang, Wei Qin   +12 more
doaj   +1 more source

Bilirubin production and hour-specific bilirubin levels [PDF]

Journal of Perinatology, 2015
We assessed the relative contributions of increased bilirubin production (indexed by end-tidal carbon monoxide (CO) concentrations, corrected for ambient CO (ETCOc)) to hour-specific total bilirubin (TB) levels in healthy late preterm and term newborns.Post hoc analyses of concurrent ETCOc and TB (at 30±6 h of age) and follow-up TB levels at age 96±12 ...
V K, Bhutani, R J, Wong, H J, Vreman, D K, Stevenson   +3 more
openaire   +2 more sources

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Bilirubin-human serum albumin interaction monitored by capillary zone electrophoresis

, 1999
Capillary zone electrophoresis was used to monitor the interaction between bilirubin and human serum albumin. Cord blood serum samples were injected directly into an uncoated fused-silica capillary (30 cm x 50 μm i.d.) and separation was accomplished ...
Lau, KM, Fung, Y, Fung, YS, Zhang, B, Lin, B, Lau, K, Lin, BC   +6 more
core   +1 more source

Bilirubin and cardiovascular risk

, 2021
This literature review demonstrates the results of experimental and clinical studies, as well as data from meta-analyzes on the effect of bilirubin levels on cardiovascular system.
A. V. Budnevsky, T. A. Chernik, A. Ya. Kravchenko, A. V. Kontsevaya, M. S. Ryaskina, O. M. Drapkina   +5 more
core   +1 more source

External Drainage of Giant Infantile Choledochal Cyst before Definitive Repair: Is it Worth? [PDF]

Journal of Clinical and Diagnostic Research, 2017
Infantile Choledochal Cysts (IFCC) usually present with jaundice, acholic stool and abdominal lump or abdominal distension. If the surgical intervention is delayed, they rapidly progress to liver fibrosis which is considered to be irreversible if ...
Vijai Datta Upadhyaya, Basant Kumar, Sandeep Kumar Raut, Eti Sthapak   +3 more
doaj   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

CRIGLER- NAJJAR SYNDROME – CASE REPORT

Slovenska pediatrija, 2022
Crigler-Najjar syndrome is a rare genetic disorder that causes severe unconjugated hyperbilirubinaemia. The syndrome is caused by a mutation in the UGT1A1 gene, which results in a deficiency or complete lack of the UGT1A1 enzyme, which is responsible for
Anja Šelih, Manca Velkavrh
doaj   +1 more source