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<i>Rhodiola rosea</i>, <i>Ginkgo biloba</i>, and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders. [PDF]
Li X +7 more
europepmc +1 more source
Identification of a central regulator of ginkgolide biosynthesis in <i>Ginkgo biloba</i> that integrates jasmonate and light signaling. [PDF]
Du J +15 more
europepmc +1 more source
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BILOBALIDE AND NEUROPROTECTION
Pharmacological Research, 2002In vivo studies have indicated that systemically administered bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba leaf extracts, can reduce cerebral edema produced by triethyltin, decrease cortical infarct volume in certain stroke models, and reduce cerebral ischemia.
Francis V Defeudis
exaly +3 more sources
Effect of bilobalide on peripheral nerve regeneration
Biomaterials, 2004The present study provides in vivo trials of silicone rubber chambers filled with different concentrations of bilobalide (0, 50, 100, 200, 400 microM) to bridge a 15 mm sciatic nerve defect in rats. Collagen was also filled in the chambers to prevent the bilobalide from leakage. Histological and electrophysiological techniques were used to evaluate the
Yueh-Sheng Chen, Chun-Hsu Yao
exaly +3 more sources
Bilobalide: A review of its pharmacology, pharmacokinetics, toxicity, and safety
Phytotherapy Research, 2021Bilobalide is a natural sesquiterpene trilactone from Ginkgo biloba leaves. It has good water solubility and is widely used in food and pharmaceutical fields. In the last decade, a plethora of studies on the pharmacological activities of bilobalide has been conducted and demonstrated that bilobalide possessed an extensive range of pharmacological ...
Jing Lu, Long Xie, Jing Lu
exaly +3 more sources
Protection of mitochondrial respiration activity by bilobalide
Biochemical Pharmacology, 1999Mitochondria alteration is an early event in ischemia-induced damage, and its prevention improves tissue survival upon reperfusion. Adenine translocase and complex I activities are rapidly affected by ischemia. Ginkgo biloba extract demonstrates anti-ischemic properties attributable to the terpenoid fraction, mainly due to the presence of bilobalide ...
Carine Michiels, José Remacle, K Drieu
exaly +5 more sources

