Results 151 to 160 of about 1,516 (196)

Ginkgolides and Bilobalide: Their Physical, Chromatographic and Spectroscopic Properties

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Beek, T.A., van, van Beek, T.A.
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Protective and therapeutic role of Bilobalide in cuprizone-induced demyelination

International Immunopharmacology, 2019
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system characterized by recurrent and progressive demyelination, neuroinflammation and oligodendrocyte loss. The cuprizone (CPZ) model is characterized by primary and reversible demyelination, accompanied by oligodendrocyte loss and neuroinflammation. In the current study,
Cun-gen Ma, Bao-Guo Xiao, Jing-Wen Yu
exaly   +3 more sources

The alleviating effect and mechanism of Bilobalide on ulcerative colitis

Food & Function, 2021
Bilobalide alleviates ulcerative colitis by inhibiting inflammatory response, protecting the intestinal epithelial barrier, and improving the composition of intestinal flora.
Haolong Zhang, Yan Wang, Yingchun Su, Xuedong Fang, Wenjin Guo   +4 more
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Neuroprotection by bilobalide in ischemia: Improvement of mitochondrial function

Die Pharmazie, 2013
Bilobalide, an active constituent of Ginkgo biloba, is known to have neuroprotective properties, but its mode of action remains unclear. In this study, bilobalide significantly reduced brain damage in mice (indicated by TTC staining) when given before transient middle cerebral artery occlusion (tMCAO).
T M, Schwarzkopf, S, Hagl, G P, Eckert, J, Klein   +3 more
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Regeneration of Motor Nerves in Bilobalide-Treated Rats

Planta Medica, 1993
Bilobalide, a terpene extracted from the leaves of the Ginkgo biloba tree, has been proposed to exert trophic and protective effects on neurons and on Schwann's cells in various neuropathies. The reinnervation of the extensor digitorum longus muscle following traumatic nerve damage was investigated in rats by using electrophysiological and histological
BRUNO, CESARE, CUPPINI, RICCARDO, SARTINI, STEFANO, CECCHINI, TIZIANA, AMBROGINI, PATRIZIA, BOMBARDELLI E.   +5 more
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Photochemical Approaches to the Bilobalide Core

European Journal of Organic Chemistry, 2017
Bilobalide is a tetracyclic sesquiterpene containing three contiguous γ‐lactone rings and an unusual tert‐butyl group, which is found in the leaves of the ginkgo tree (Ginkgo biloba). Three different photochemical approaches towards bilobalide's unique skeleton are presented.
Jens Emsermann, Till Opatz
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Chemie der Ginkgolide, III. Bilobalid/iso‐Bilobalid – Strukturbeweis durch Röntgenbeugung

Liebigs Annalen der Chemie, 1987
AbstractBilobalid (1a) zeigt auffallende biologische Wirkungen und ungewöhnliche chemische Eigenschaften. Ausgeprägt ist seine Tendenz, unter gelinden Acylierungsbedingungen zu den Diacyl‐Derivaten 2e–g der Spiro‐Verbindung 2a zu isomerisieren. Die Strukturen von Bilobalid (1a) und 10,12‐Di‐O‐pivaloyl‐iso‐bilobalid (2f) werden durch Röntgenbeugung ...
Klaus Weinges, Michael Hepp, Ursula Huber‐Platz, Hermann Irngartinger   +3 more
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Effects of Bilobalide on Cerebral Amino Acid Neurotransmission

Pharmacopsychiatry, 2003
Bilobalide is one of many active constituents found in EGb 761 (definition see editorial), which is extracted from Ginkgo biloba leaves. Whilst there is good, sound evidence that bilobalide exhibits neuroprotective actions in a variety of model systems, there is currently no consensus on its mechanism of action.
J A, Davies, L, Johns, F A, Jones
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Bilobalide and PC12 cells: A structure activity relationship study

Bioorganic & Medicinal Chemistry, 2020
Ginkgo biloba extracts have been postulated to beneficial for improving cognitive function and as such they have been used as a potential treatment of Alzheimer's disease. The main active ingredients of the extract are terpene trilactones (TTLs), such as bilobalide (BB) and ginkgolides.
Toyonobu, Usuki, Yukiko, Yoshimoto, Makiko, Sato, Tae, Takenaka, Ryota, Takezawa, Yusuke, Yoshida, Masayuki, Satake, Noriyuki, Suzuki, Daisuke, Hashizume, Sergei V, Dzyuba   +9 more
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ChemInform Abstract: A Total Synthesis of (.+‐.)‐Bilobalide.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. T. CRIMMINS, D. K. JUNG, J. L. GRAY
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