Results 81 to 90 of about 294,501 (380)

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

open access: yesAdvanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang   +13 more
wiley   +1 more source

Bridge Digital Twin for Practical Bridge Operation and Maintenance by Integrating GIS and BIM

open access: yesBuildings
As an emerging technology, digital twin (DT) is increasingly valued in bridge management for its potential to optimize asset operation and maintenance (O&M). However, traditional bridge management systems (BMS) and existing DT applications typically rely
Yan Gao   +4 more
doaj   +1 more source

Analysis and Discussion on the Design of Green Super High-rise Civil Buildings in Huangshan [PDF]

open access: yesE3S Web of Conferences, 2019
With the accelerating urbanization process and the development of the construction industry, the role of green building design in architectural design is constantly reflected.
Jun Liu   +4 more
doaj   +1 more source

A technical review of BIM based cost estimating in UK quantity surveying practice, standards and tools [PDF]

open access: yes, 2014
In light of recent technological advancements over the decades especially with Information Technology (IT), the ‘Building Information Modelling’ (BIM) is one of those advancements that have attracted significant attentions in UK construction industry ...
Ginige, Kanchana   +3 more
core  

Design for safety: theoretical framework of the safety aspect of BIM system to determine the safety index [PDF]

open access: yes, 2016
Despite the safety improvement drive that has been implemented in the construction industry in Singapore for many years, the industry continues to report the highest number of workplace fatalities, compared to other industries.
Kim, Hanjoon   +3 more
core   +3 more sources

BIM-Based End-of-Lifecycle Decision Making and Digital Deconstruction: Literature Review

open access: yes, 2020
This article is the second part of a two-part study, which explored the extent to which Building Information Modelling (BIM) is used for End-of-Lifecycle (EoL) scenario selection to minimise the Construction and Demolition Waste (CDW).
Arghavan Akbarieh   +3 more
semanticscholar   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

open access: yesAdvanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong   +6 more
wiley   +1 more source

PEMAHAMAN KOMPETENSI PARENTING TERHADAP PERKEMBANGAN SOSIAL ANAK (STUDI KASUS PADA KELOMPOK BERMAIN DI PAKEM, SLEMAN)

open access: yesJurnal Pendidikan dan Pemberdayaan Masyarakat, 2014
Penelitian ini bertujuan untuk memahami kompetensi parenting orangtua, kendala dalam pengasuhan, dan strategi yang dilakukan. Penelitian ini merupakan penelitian kualitatif dengan subjek penelitian orangtua peserta didik pada lembaga kelompok bermain di ...
Haryanti Haryanti, Sumarno Sumarno
doaj  

Internal Mission by St Nicholas the Wonderworker Brotherhood in Vyatka in the late XIX and early XX Century [PDF]

open access: yesВестник Свято-Филаретовского института, 2015
The article reviews and analyses the missionary and educational work carried out by St Nicholas the Wonderworker Brotherhood in Vyatka, founded by Archpriest Stefan Kashmensky in 1882. The Brotherhood was engaged in educating the Old Believers population
Ekaterina Bim
doaj  

Inhibition of glucocorticoid-induced apoptosis by targeting splice variants of \u3ci\u3eBIM\u3c/i\u3e mRNA with small interfering RNA and short hairpin RNA. [PDF]

open access: yes, 2004
Glucocorticoids (GCs) induce apoptosis in lymphocytes and are effective agents for the treatment of leukemia. The activated glucocorticoid receptor (GR) initiates a transcriptional program leading to caspase activation and cell death, but the critical ...
Abrams, Marc T.   +3 more
core   +1 more source

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