Results 11 to 20 of about 2,291 (216)
The Formation of Close Binaries [PDF]
Symposium - International Astronomical Union, 1980 Although the formation of close binaries has been the subject of numerous investigations in the last 100 years (for a recent review, see Tassoul 1978), we cannot yet claim decisive observational support for any theory, a state of affairs probably reflecting insufficient development of the various theories, rather than a failure to propose the correct ...
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Close binary system GO Cyg [PDF]
New Astronomy, 2012 In this study, we present long term photometric variations of the close binary system \astrobj{GO Cyg}. Modelling of the system shows that the primary is filling Roche lobe and the secondary of the system is almost filling its Roche lobe. The physical parameters of the system are $M_1 = 3.0\pm0.2 M_{\odot}$, $M_2 = 1.3 \pm 0.1 M_{\odot}$, $R_1 = 2.50 ...
Ulas, B. +4 more
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Close Binary Perspectives [PDF]
Galaxies, 2020 Development of analytic binary star models is discussed in historical and on-going perspective, beginning with an overview of paradigm shifts, the merits of direct (rectification-free) models, and fundamental four-type binary system morphology. Attention is called to the likelihood that many or even most cataclysmic variables may be of the double ...
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
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NONLINEAR TIDES IN CLOSE BINARY SYSTEMS [PDF]
The Astrophysical Journal, 2012 40 pages, 16 figures. Matches version published in ApJ; conclusions unchanged; some restructuring of sections; sect. 5 now provides simple physical estimates of the nonlinear growth rates that agree well with the detailed calculations given in the ...
Weinberg, Nevin N. +3 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
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Evolution of Close Binaries [PDF]
Symposium - International Astronomical Union, 1981 Most stars of our Galaxy's disk are double. The existing estimation of duplicity ααrange from ~ 50-70 % (Abt, Levy, 1976, Abt, 1979) to ~ 100 % (Kraitcheva et al., 1978). About half of all stars are close binaries (CB) and hence their components fill their Roche lobes during evolution.
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