Results 21 to 30 of about 5,637 (264)
Rotation in Close Binaries [PDF]
Symposium - International Astronomical Union, 1980 It has been demonstrated (Zahn 1966 a, b, c; 1975, 1977) that turbulent viscous dissipation of tides can brake the rotation of stars having convective envelopes, while radiative dissipation can do like-wise for those having radiative envelopes. The time scales for the former are very small whereas those for the latter depend sensitively on the ratio r ...
R. Rajamohan, P. Venkatakrishnan
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Detection Rates for Close Binaries via Microlensing [PDF]
, 1997 Microlensing is one of the most promising methods of reconstructing the stellar mass function down to masses even below the hydrogen-burning limit. The fundamental limit to this technique is the presence of unresolved binaries, which can, in principle ...
Gaudi, B. Scott, Gould, Andrew
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Enhanced Activity in Close T Tauri Binaries
, 2006 The number of confirmed and suspected close T Tauri binaries (period days) is increasing. We discuss some systems with enhanced emission line activity and periodic line profile changes.
Gahm, Gösta,
core +1 more source
Close Binary Perspectives [PDF]
Galaxies, 2020 Development of analytic binary star models is discussed in historical and on-going perspective, beginning with an overview of paradigm shifts, the merits of direct (rectification-free) models, and fundamental four-type binary system morphology. Attention is called to the likelihood that many or even most cataclysmic variables may be of the double ...
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2012 Globular clusters (GCs) effectively produce dynamically formed low-mass X-ray binaries (LMXBs). Observers detect ~100 times more LMXBs per stellar mass in GCs compared to stars in the fields of galaxies.
Fabbiano, Guiseppina +8 more
core +1 more source