Results 11 to 20 of about 2,448 (242)

Visual Binary Stars: Data to Investigate Formation of Binaries

open access: yesOpen Astronomy, 2016
Abstract Statistics of orbital parameters of binary stars as well as statistics of their physical characteristics bear traces of star formation history. However, statistical investigations of binaries are complicated by incomplete or missing observational data and by a number of observational selection effects.
Dana Kovaleva   +3 more
openaire   +4 more sources

Some spectroscopic observations of visual binaries [PDF]

open access: yesAstrophysics and Space Science, 1965
AbstractThe use of a coudé spectrograph for securing the high-resolution spectrograms necessary to follow the slow variations of radial velocity exhibited by visual binaries is discussed. Recent observations, using the spectrograph at the coudé focus of the Dominion Astrophysical Observatory’s 48-in. reflector, are then presented for the systems ofαUMa,
openaire   +3 more sources

Multiplicity among Visual Binaries [PDF]

open access: yesInternational Astronomical Union Colloquium, 1977
AbstractA brief review of the history of multiple-star discovery is followed by a discussion of selection effects, discovery probability, and detection techniques. The incidence of multiplicity and the properties of multiples in various samples of binaries are investigated.
openaire   +2 more sources

The Census of Exoplanets in Visual Binaries

open access: yes, 2021
While numerous exoplanets have now been uncovered in stellar binaries, the impact of companion stars on planet formation and evolution is still not understood. From the Gaia DR2 catalog and an extensive literature search, we compiled the largest list to date of planets orbiting stars in visual comoving binaries out to 200 pc, providing a broad overview
Fontanive, Clémence   +1 more
openaire   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh   +22 more
wiley   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim   +6 more
wiley   +1 more source

Analysis of Soluble Interleukin‐2 Receptor as a Prognostic Biomarker in NMOSD and MOGAD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Soluble interleukin‐2 receptor (sIL‐2R) is a biomarker for T cell activity. T cells are involved in neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) pathogenesis. However, sIL‐2R has so far not been evaluated in these conditions.
Philipp Klyscz   +8 more
wiley   +1 more source

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