Results 91 to 100 of about 33,048 (289)

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Improved Degraded Document Image Binarization Using Median Filter for Background Estimation

Elektronika ir Elektrotechnika, 2018
In this paper, we propose a new binarization method suitable for images having a variety of sizes and degradation levels. It is mainly based on the idea of estimating a document background surface by new smoothing approach through a median filter and ...
Mehdi Khitas, Lahcene Ziet, Saad Bouguezel   +2 more
doaj   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

Method for quickly building road network model of open-pit mine based on grid refinement

Meitan xuebao
Constructing the road network in open-pit mining areas is a crucial step for intelligent scheduling and autonomous driving of trucks in these regions. However, given the intricate road conditions, extensive GPS trajectory data from mining vehicles, and ...
Qinghua GU, Fengyuan HU, Qian WANG, Xiaobo CHAI, Dan WANG, Xinxin JING   +5 more
doaj   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

ECM‐Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling

Advanced Science, EarlyView.
Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy, Oscar André, Zhimeng Fan, Pontus Nordenfelt, Vinay S Swaminathan   +4 more
wiley   +1 more source

Image-Based Phenotyping Framework for Blackleg Disease in Canola: Progressing towards High-Throughput Analyses via Individual Plant Extraction

AgriEngineering
Crop diseases are a significant constraint to agricultural production globally. Plant disease phenotyping is crucial for the identification, development, and deployment of effective breeding strategies, but phenotyping methodologies have not kept pace ...
Saba Rabab, Luke Barrett, Wendelin Schnippenkoetter, Rebecca Maher, Susan Sprague   +4 more
doaj   +1 more source

Handheld Mobile Device Based Text Region Extraction and Binarization of Image Embedded Text Documents

Journal of Intelligent Systems, 2013
Effective text region extraction and binarization of image embedded text documents on mobile devices having limited computational resources is an open research problem.
Mollah Ayatullah Faruk, Basu Subhadip, Nasipuri Mita, Basu Dipak Kumar   +3 more
doaj   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source