Results 41 to 50 of about 2,337,681 (280)

Binary-black-hole initial data with nearly-extremal spins [PDF]

open access: yes, 2008
There is a significant possibility that astrophysical black holes with nearly-extremal spins exist. Numerical simulations of such systems require suitable initial data.
Chu, Tony   +3 more
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Local binary pattern‐based reversible data hiding

open access: yesCAAI Transactions on Intelligence Technology, 2022
A novel local binary pattern‐based reversible data hiding (LBP‐RDH) technique has been suggested to maintain a fair symmetry between the perceptual transparency and hiding capacity. During embedding, the image is divided into various 3×3 blocks.
Monalisa Sahu   +3 more
doaj   +1 more source

Simplified, high-speed binary data decoder [PDF]

open access: yes, 1968
Simplified, high-speed decoder of encoded binary data received over a noisy channel is provided in a versatile apparatus that can accommodate more than one particular set of codes.
Anderson, T. O.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Model parameter estimation with imprecise information

open access: yesWater Science and Technology
Model parameter estimation is a well-known inverse problem, as long as single-value point data are available as observations of system performance measurement.
Wolfgang Rauch   +2 more
doaj   +1 more source

A binary biclustering algorithm based on the adjacency difference matrix for gene expression data analysis

open access: yesBMC Bioinformatics, 2022
Biclustering algorithm is an effective tool for processing gene expression datasets. There are two kinds of data matrices, binary data and non-binary data, which are processed by biclustering method.
He-Ming Chu   +5 more
doaj   +1 more source

Initial data transients in binary black hole evolutions

open access: yes, 2011
We describe a method for initializing characteristic evolutions of the Einstein equations using a linearized solution corresponding to purely outgoing radiation.
Babiuc M   +12 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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