Results 51 to 60 of about 2,337,681 (280)
Constant Information Design for Binary Response Data
Sultan Qaboos University Journal for Science, 1998 A major problem is designing experiments when the assumed model is nonlinear, is the dependence of the designs on the values of the unknown parameters we consider in this article designs for binary data and generalize the constant information criterion ...
K.A. Abdelbasit
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A joint regression modeling framework for analyzing bivariate binary data in R
Dependence Modeling, 2017 We discuss some of the features of the R add-on package GJRM which implements a flexible joint modeling framework for fitting a number of multivariate response regression models under various sampling schemes.
Marra Giampiero, Radice Rosalba
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Multilevel Cross-Dependent Binary Longitudinal Data [PDF]
Biometrics, 2013 Summary We provide insights into new methodology for the analysis of multilevel binary data observed longitudinally, when the repeated longitudinal measurements are correlated. The proposed model is logistic functional regression conditioned on three latent processes describing the within- and between-variability, and describing the ...
Serban, Nicoleta +2 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Robust Inference with Binary Data [PDF]
Psychometrika, 2002 In this paper robustness properties of the maximum likelihood estimator (MLE) and several robust estimators for the logistic regression model when the responses are binary are analysed. It is found that the MLE and the classical Rao's score test can be misleading in the presence of model misspecification which in the context of logistic regression ...
openaire +5 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Lightweight Neural Network for Holographic Reconstruction of Pseudorandom Binary Data
TechnologiesNeural networks are a state-of-the-art technology for fast and accurate holographic image reconstruction. However, at present, neural network-based reconstruction methods are predominantly applied to objects with simple, homogeneous spatial structures ...
Mikhail K. Drozdov +10 more
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