Results 31 to 40 of about 1,303,019 (294)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modeling Transport Mode Decisions Using Hierarchical Binary Spatial Regression Models with Cluster Effects [PDF]

open access: yes, 2004
This work is motivated by a mobility study conducted in the city of Munich, Germany. The variable of interest is a binary response, which indicates whether public transport has been utilized or not.
Czado, Claudia, Prokopenko, S.
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Binary to binary coded decimal converter [PDF]

open access: yes, 1978
A binary coded input signal is converted to a binary coded decimal signal having N decades by employing N four bit shift registers. The bits of the input signal are sequentially supplied, in order, to the least significant position of the register for ...
Miller, A. J.
core   +1 more source

Generalized extreme value regression for binary response data: An application to B2B electronic payments system adoption

open access: yes, 2011
In the information system research, a question of particular interest is to interpret and to predict the probability of a firm to adopt a new technology such that market promotions are targeted to only those firms that were more likely to adopt the ...
Dey, Dipak K., Wang, Xia
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Multi-stage Optional Unrelated Question RRT Model [PDF]

open access: yesJournal of Statistical Theory and Applications (JSTA), 2016
Sihm et al. (2014) introduced modified optional unrelated question RRT model in both binary and quantitative response situations wherein the prevalence of the sensitive variable and the sensitivity level of the underlying sensitive question could be ...
Anu Chhabra, B.K. Dass, Samridhi Mehta
doaj   +1 more source

Bayesian sequential experimental design for binary response data with application to electromyographic experiments [PDF]

open access: yes, 2014
We develop a sequential Monte Carlo approach for Bayesian analysis of the experimental design for binary response data. Our work is motivated by surface electromyographic (SEMG) experiments, which can be used to provide information about the ...
Azadi, Nammam Ali   +3 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Response-Based Sampling for Binary Choice Models With Sample Selection

open access: yesEconometrics, 2018
Sample selection models attempt to correct for non-randomly selected data in a two-model hierarchy where, on the first level, a binary selection equation determines whether a particular observation will be available for the second level (outcome equation)
Maria Felice Arezzo   +1 more
doaj   +1 more source

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