Results 71 to 80 of about 1,454,218 (304)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Solubility of Anthracene and Pyrene in Binary Alcohol + Alcohol Solvent Mixtures [PDF]

, 1995
Article on the solubility of anthracene and pyrene in binary alcohol + alcohol solvent ...
Powell, Joyce R., Kauppila, Ann-Sofi M., Zvaigzne, Anita I., McHale, Mary E. R., Acree, William E. (William Eugene)   +4 more
core   +1 more source

A SIMPLE MODEL FOR THE ESTIMATION OF DIELECTRIC CONSTANTS OF BINARY SOLVENT MIXTURES [PDF]

Journal of Sciences, Islamic Republic of Iran, 1997
A simple and reliable method for quick estimation of the dielectric constant of a binary solvent mixture is proposed.
doaj  

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Solubility of Anthracene in Binary Alcohol + 2-Methoxyethyl Ether Solvent Mixtures [PDF]

, 1997
Article on the solubility of anthracene in binary alcohol + 2-methoxyethyl ether solvent ...
Powell, Joyce R., Coym, Karen S., Acree, William E. (William Eugene)   +2 more
core   +1 more source

Development of Extractive Distillation Processes for Close-Boiling Polar Systems

Chemical Engineering Transactions, 2018
Extractive distillation is a distillation technique that can be applied for separation of azeotropic mixtures and mixtures of close-boiling compounds. In extractive distillation a solvent is applied to increase the relative volatility by interacting with
Lisette Sprakel, Peter Kamphuis, Anna Nikolova, Boelo Schuur   +3 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Solubility of Anthracene in Binary Alcohol + 2-Ethyl-1-hexanol Solvent Mixtures [PDF]

, 1995
Article on the solubility of anthracene in binary alcohol + 2-ethyl-1-hexanol solvent ...
Powell, Joyce R., Kauppila, Ann-Sofi M., Otero, Pablo, Jayasekera, Melani, McHale, Mary E. R., Acree, William E. (William Eugene)   +5 more
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source