ProteinDJ: A high-performance and modular protein design pipeline. [PDF]
Silke D +6 more
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Dynamic Binder Exchange Improves Protein Labeling Efficiency in DNA-PAINT up to 15-Fold. [PDF]
Steinek C +5 more
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Characterization of Viscoelastic Performance and VOC Emission of Warm-Mixed SBS Asphalt Binder Under Different Dosages of Warm-Mixed Additive. [PDF]
Wang W +5 more
europepmc +1 more source
Bio-synthesized TiO2 nanoparticles and the aqueous binder-based anode derived thereof for lithium-ion cells [PDF]
Akhilash Mohanan Pillai +6 more
openalex +1 more source
Pushing The Limits Of Detection Of Weak Binding Using Fragment Based Drug Discovery: Identification Of New Cyclophilin Binders [PDF]
C. Georgiou +5 more
openalex +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The mechanical and microstructural characteristics of low-energy calcined clay from a high-Egyptian gray clay with hydrated lime for rendering mortar applications. [PDF]
Salama KS +5 more
europepmc +1 more source

