Results 171 to 180 of about 224,890 (308)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Synthesis of Dopamine-Modified Sodium Alginate as a Binder for Nanosilicon Anode in Lithium Ion Battery

The potential of silicon as the anode material of future high-capacity lithium-ion batteries is still difficult to realize due to the low mobility of electrons and the material's vulnerability to damage from considerable volume expansion. The development
Pandiangan, Josua
core  

Abdominal binders versus semi-rigid corsets after open ventral hernia repair: early postoperative tolerance and patient preference in a randomized cross-over study. [PDF]

Hernia
Mitura K, Pajer M, Kacprzak L, Niecikowski P, Wojcik M, Mitura L, Sawicka M, Witowska I, Kisielewski K.   +8 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Large Section Ceramic Injection Moulding

, 2000
PhDCeramic injection moulding is already established as a production technique for complex shaped ceramic components. However the process is limited to thin section mouldings generally not exceeding a wall thickness of 10 mm.
Krug, S., Krug, Steffen
core  

A Critical Appraisal of Pyrolysis Pretreatment in Lithium-Ion Battery Recycling: From High-Temperature Material Transformations to Environmental Impact. [PDF]

ChemSusChem
Saeed M, Klemettinen L, Klemettinen A, Serna-Guerrero R.   +3 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Integrative evaluation of utilization the nanomaterials as a modifier to asphalt mixtures: traditional and Superpave tests. [PDF]

Sci Rep
Ragab M, Kotb SA, Afify HA, Abo El-Naga I.   +3 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

ANALYSIS OF INTERNAL POROSITIES AND DENSITY ENHANCEMENT METHODS IN AISI 316L SAMPLES OBTAINED BY BINDER-JETTING

reservedBinder-Jetting is an additive manufacturing process characterized by a layer approach, used to produce prototypes or small production series. Polymeric ink is selectively deposited on a metallic powder bed, then the entire volume is put inside a ...
FOGAGNOLO, ANDREA
core