Results 61 to 70 of about 4,288,984 (317)
While the majority of the contributions to this blog symposium tackle issues of global justice, distributive justice and the impact of a decolonial perspective on global health law, our approach might seem to stand out at first sight: Our contribution is interested in the legal form the new Pandemic Agreement will take.
Aust, Helmut Philipp, Schott, Felix
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Outer Membrane Protein YadA of Enteropathogenic Yersiniae Mediates Specific Binding to Cellular but Not Plasma Fibronectin [PDF]
, 1993 The binding of bacteria or bacterial products to host proteins of tissue extracellular matrix may be a mechanism of tissue adherence. We investigated interactions of the plasmid-encoded outer membrane protein YadA, which confers pathogenic functions on ...
Emmerich, F. +7 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Journal of Biomedical Science, 2012 Background Platelet-derived growth factor (PDGF) is a potent stimulator of growth and motility of vascular smooth muscle cells (VSMCs). Abnormalities of PDGF/PDGF receptor (PDGFR) are thought to contribute to vascular diseases and malignancy.
Lo Huey-Ming +4 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Variable structure motifs for transcription factor binding sites [PDF]
, 2010 Background: Classically, models of DNA-transcription factor binding sites (TFBSs) have been based on relatively few known instances and have treated them as sites of fixed length using position weight matrices (PWMs).
Evans, Kenneth J. +17 more
core +1 more source
Donkey anaphora is in-scope binding
Semantics and Pragmatics, 2008 We propose that the antecedent of a donkey pronoun takes scope over and binds the donkey pronoun, just like any other quantificational antecedent would bind a pronoun.
Chris Barker, Chung-chieh Shan
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The interpretative options of anaphoric complex demonstratives
Glossa, 2022 In this paper, we present experimental evidence from a ‘yes’/‘no’ judgement task and two acceptability rating studies (Experiments 1a-c) for the claim made in Hinterwimmer (2019) that sentences with two anaphorically interpreted complex demonstratives ...
Stefan Hinterwimmer, Umesh Patil
doaj +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source