Results 41 to 50 of about 6,725,434 (301)

Public health careers: mapping information, informing practitioner needs [PDF]

open access: yes, 2016
Public health promotion and ill health prevention is a key priority for the NHS. The public health workforce is central to achieving improved health outcomes for a diverse and changing population.
Binding, Charlene   +2 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

S100 Proteins—Intracellular and Extracellular Function in Norm and Pathology

open access: yesBiomolecules
The S100 proteins are small, ubiquitous, mostly homodimeric proteins containing two EF-hand structures, that is, helix-loop-helix motifs specialized in high-affinity calcium-binding (~10−6 M) [...]
Wiesława Leśniak, Anna Filipek
doaj   +1 more source

Reflexivity and adjustment strategies at the interfaces

open access: yesNordlyd: Tromsø University Working Papers on Language & Linguistics, 2011
I argue in this work that Reinhart & Reuland’s (1993) conditions A and B hold for Spanish. I provide evidence supporting the hypothesis that this language makes use of both SE and SELF-anaphors.
Ismael Teomiro
doaj   +1 more source

Nähe der Antike : eine Ansprache [PDF]

open access: yes, 2010
Frankfurter gelehrte Reden und Abhandlungen VIII. Heft : Zwei Ansprachen zur Eröffnung der Ortsgruppe Frankfurt am Main der Gesellschaft für antike Kultur am 9. Dezember 1925 Nähe der Antike / Rudolf G. Binding Zeit und Antike / W.
Binding, Rudolf G.
core  

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

MSALigMap—A Tool for Mapping Active-Site Amino Acids in PDB Structures onto Known and Novel Unannotated Homologous Sequences with Similar Function

open access: yesLife, 2022
MSALigMap (Multiple Sequence Alignment Ligand Mapping) is a tool for mapping active-site amino-acid residues that bind selected ligands on to target protein sequences of interest.
Sameer Hassan   +3 more
doaj   +1 more source

An interview with Paul Binding [PDF]

open access: yes, 2015
Paul Binding is a British writer who has worked in many fields: he is a literary critic, novelist, reviewer and renowned expert in Scandinavian literature.
Paul Binding, Turner, Nick
core  

Survey of variation in human transcription factors reveals prevalent DNA binding changes [PDF]

open access: yes, 2016
Published in final edited form as: Science. 2016 Mar 25; 351(6280): 1450–1454. Published online 2016 Mar 24. doi: 10.1126/science.aad2257Sequencing of exomes and genomes has revealed abundant genetic variation affecting the coding sequences of human ...
Barrera, Luis A.   +21 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

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