PocketPicker: analysis of ligand binding-sites with shape descriptors [PDF]
, 2007 Background Identification and evaluation of surface binding-pockets and occluded cavities are initial steps in protein structure-based drug design.
Weisel, Martin +2 more
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Subject-Object binding dependencies in Romanian
LingBaW, 2023 This paper dwells on an interesting contrast between Romance (Romanian, Spanish a.o.) and Germanic languages (English, German a.o.) with respect to the syntax and the interpretation of the direct object (DO).
Alina Tigău
doaj +1 more source
Phosphate‐binding sequences in nucleotide‐binding proteins [PDF]
FEBS Letters, 1985 In the three‐dimensional model of adenylate kinase, the phosphate‐binding site for AMP and ATP has been identified [Pai, E.F. et al. (1977) J. Mol. Biol. 114, 37‐45]. In this region one can distinguish a sequence glycine XXXX glycinelysine. The same sequence is found in many other mononucleotide‐binding proteins including elongation factors and ...
Möller, W., Amons, R.
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Binding kinetics of membrane-anchored receptors and ligands: molecular dynamics simulations and theory [PDF]
, 2015 The adhesion of biological membranes is mediated by the binding of membrane-anchored receptor and ligand proteins. Central questions are how the binding kinetics of these proteins is affected by the membranes and by the membrane anchoring of the proteins.
Hu, Jinglei +3 more
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Remote Sensing, 2019 Red and near-infrared line-height algorithms such as the maximum chlorophyll index (MCI) are often considered optimal for remote sensing of chlorophyll-a (Chl-a) in turbid eutrophic waters, under the assumption of minimal influence from mineral sediments.
Chuiqing Zeng, Caren Binding
doaj +1 more source
Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. [PDF]
, 2018 Tight binding of Gdown1 represses RNA polymerase II (Pol II) function in a manner that is reversed by Mediator, but the structural basis of these processes is unclear.
A Leitner +56 more
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Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression [PDF]
, 2017 Cells may control fluctuations in protein levels by means of negative autoregulation, where transcription factors bind DNA sites to repress their own production.
Lengyel, Iván M., Morelli, Luis G.
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Influence of arousal on intentional binding: Impaired action binding, intact outcome binding [PDF]
Attention, Perception, & Psychophysics, 2020 AbstractEmotional states have been indicated to affect intentional binding, resulting in an increase or decrease as a function of valence and arousal. Sexual arousal is a complex emotional state proven to impair attentional and perceptual processes, and is therefore highly relevant to feeling in control over one’s actions.
Render, Anna, Jansen, Petra
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Peptide Inhibitors of Vascular Endothelial Growth Factor A: Current Situation and Perspectives
Pharmaceutics, 2021 Vascular endothelial growth factors (VEGFs) are the family of extracellular signaling proteins involved in the processes of angiogenesis. VEGFA overexpression and altered regulation of VEGFA signaling pathways lead to pathological angiogenesis, which ...
Ivan Guryanov +2 more
doaj +1 more source
De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. [PDF]
, 2014 The splicing regulator Polypyrimidine Tract Binding Protein (PTBP1) has four RNA binding domains that each binds a short pyrimidine element, allowing recognition of diverse pyrimidine-rich sequences.
Black, Douglas L +5 more
core +4 more sources