Results 11 to 20 of about 4,288,984 (317)
Epigenetic Regulation of Epidermal Differentiation
Epigenomes, 2021 The epidermis is the outer part of the skin that protects the organism from dehydration and shields from external insults. Epidermal cells, called keratinocytes, undergo a series of morphological and metabolic changes that allow them to establish the ...
Wiesława Leśniak
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To bind or not to bind: potassium-lowering drugs in heart failure [PDF]
European Heart Journal, 2011 This editorial refers to ‘Evaluation of the efficacy and safety of RLY5016, a polymeric potassium binder, in a double-blind, placebo-controlled study in patients with chronic heart failure (the PEARL-HF) trial’[†][1], by B. Pitt et al. , on page 820 More than a decade ago the first large randomized controlled trial studying the effects of ...
van der Meer, Peter +1 more
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Replication data for: The Comparative Meaning of Political Space: A Comprehensive Modeling Approach
, 2023 In latent scaling applications, such as the positioning of political parties, differential item functioning (DIF) may occur because of measurement issues or because of substantive differences in the association between latent and manifest variables ...
Steenbergen, Marco +2 more
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Home Economics at Swiss Secondary Schools (HESSS)
, 2023 The Home Economics at Swiss Secondary Schools (HESSS) dataset covers the provision of home economics education in ten German-speaking cantons in Switzerland for vocational- and university track secondary schools since 1980 and 1991, respectively.
Grob, Anja +2 more
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Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components [PDF]
, 2009 In many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla.
Field, L.M. +20 more
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Pneumococcal vaccination responses in adults with subnormal IgG subclass concentrations
BMC Immunology, 2019 Background We sought to compare Pneumovax®23 responses in adults with subnormal IgG subclass concentrations. We studied adults with normal total IgG, frequent/severe respiratory infection, and subnormal IgG1, IgG3, or IgG1 + IgG3 before and after ...
Antony R. Parker +5 more
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Practical Laboratory Medicine, 2016 Objectives: Anti-pneumococcal capsular polysaccharide (PCP) IgM, IgG and IgA ELISAs have been developed to aid assessment of the adaptive immune system. The relationship between the concentrations of PCP IgM, IgG, and IgA was investigated.
Antony R. Parker +2 more
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, 2023 Das vorliegende Werk erschien als fünfter Teil des von Karl Binding herausgegebenen Werkes »Systematisches Handbuch der Deutschen Rechtswissenschaft« und ist auf zwei Bände ausgelegt.
Albert Haenel
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To Bind or Not to Bind: Unravelling GPCR Polypharmacology [PDF]
Cell, 2018 Interaction of a single drug with multiple targets through "polypharmacology" is increasingly recognized as necessary for treatment of complex diseases, such as schizophrenia. G protein-coupled receptors (GPCRs) are major medicinal targets, and understanding the structural basis of both GPCR drug selectivity and promiscuity could provide novel avenues ...
Patrick M, Sexton, Arthur, Christopoulos
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Mapping of the ligand-binding site on the b ' domain of human PDI: interaction with peptide ligands and the x-linker region [PDF]
, 2009 PDI (protein disulfide-isomerase) catalyses the formation of native disulfide bonds of secretory proteins in the endoplasmic reticulum. PDI consists of four thioredoxin-like domains, of which two contain redox-active catalytic sites (a and a'), and two ...
Freedman, R. B. +15 more
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