Results 111 to 120 of about 3,018,689 (332)

Development of Novel and Highly Specific ssDNA-Aptamer-Based Electrochemical Biosensor for Rapid Detection of Mercury (II) and Lead (II) Ions in Water

Chemosensors, 2019
In this work, we report on the development of an electrochemical biosensor for high selectivity and rapid detection of Hg2+ and Pb2+ ions using DNA-based specific aptamer probes labeled with ferrocene (or methylene blue) and thiol groups at their 5′
Hisham Abu-Ali, Alexei Nabok, Thomas J. Smith   +2 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Multiplexed Affinity Measurements of Extracellular Vesicles Binding Kinetics [PDF]

, 2021
Elisa Chiodi, George G. Daaboul, Allison M. Marn, M. Selim Ünlü   +3 more
openalex   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

In vitroandin silicoanalysis of the effects ofD₂receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations [PDF]

, 2018
Wilhelmus E. A. de Witte, Joost W Versfelt, Maria Kuzikov, Solene Rolland, Victoria Georgi, Philip Gribbon, Sheraz Gul, Dymphy Huntjens, Piet Hein van der Graaf, Meindert Danhof, Amaury E. Fernández‐Montalván, Gesa Witt, Elizabeth C. M. de Lange   +12 more
openalex   +1 more source

Exploring Microstructure–Physical Property–Corrosion Response Relationship in Intermetallic Compounds of Al‐Cu Bimetallic Interfaces

Advanced Engineering Materials, EarlyView.
Al‐Cu intermetallic compounds (IMCs) have a significant influence on the properties of Al‐Cu bimetallic interfaces formed in compound casting. This article provides a deeper understanding of microstructure, crystallography, thermal properties, hardness, and corrosion response of Al‐Cu IMCs with the goal of facilitating the optimization of the ...
Alireza Nazarahari, Tatiana Blank, Christian Hinte, Huseyin Can Ozdemir, Khemais Barienti, Christian Klose, Dermican Canadinc, Hans Jürgen Maier   +7 more
wiley   +1 more source

Trace Nickel Activated Biphasic Core‐CuOii/Shell‐CuOi Secondary Microspheres Enable Room Temperature Parts‐Per‐Trillion‐Level NO2 Detection

Advanced Engineering Materials, EarlyView.
An idea of designing novel sensors is proposed by creating appropriate Schottky barriers and vacancies between isomorphous Core‐CuOii/ Shell‐CuOi secondary microspheres and enhancing catalytic and spill‐over effects, and electronegativity via spontaneous biphasic separation, self‐assembly, and trace‐Ni‐doping.
Bala Ismail Adamu, Peipei Chen, Shafia Mukhtar Ibrahim, Mukhtar Lawan Adam, Attia Falak, Mokhotjwa Simon Dhlamini, Hanfu Wang, Lingxiang Jiang, Weiguo Chu   +8 more
wiley   +1 more source

A Positron Lifetime Study of Cooling and Natural Aging of Solutionized Aluminum Alloys

Advanced Engineering Materials, EarlyView.
The process during cooling of Al–Mg and Al–Mg–Si alloys from the solutionizing temperature down to 20 °C is interrupted. These states are analyzed with positron lifetime spectroscopy to trace the processes during cooling. In different temperature ranges, two stages of vacancy loss and solute clustering are identified.
Zi Yang, Mengjie Li, John Banhart
wiley   +1 more source

Recent Advancements in Bulk Processing of Rare‐Earth‐Free Hard Magnetic Materials and Related Multiscale Simulations

Advanced Engineering Materials, EarlyView.
This article provides an overview of recent advancements in bulk processing of rare‐earth‐free hard magnetic materials. It also addresses related simulation approaches at different scales. The research on rare‐earth‐free magnetic materials has increased significantly in recent years, driven by supply chain issues, environmental and social concerns, and
Daniel Scheiber, Andrea Bachmaier
wiley   +1 more source