Results 311 to 320 of about 3,018,689 (332)

Kinetics of oxygen binding to ferrous myeloperoxidase

Archives of Biochemistry and Biophysics, 2004
Myeloperoxidase (MPO), which is involved in host defence and inflammation, is a unique peroxidase in having a globin-like standard reduction potential of the ferric/ferrous couple. Intravacuolar and exogenous MPO released from stimulated neutrophils has been shown to exist in the oxyferrous form, called compound III.
Walter, Jantschko, Paul Georg, Furtmüller, Martina, Zederbauer, Christa, Jakopitsch, Christian, Obinger   +4 more
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Relaxation kinetics of ion binding

Journal of the Chemical Society, Faraday Transactions, 1990
The following expression is derived for the relaxation time τ associated with an ion binding equilibrium: [graphic omitted] (I) where r denotes the equilibrium forward or backward rate and where C1, Cp, m1 and C3, respectively, denote concentrations (mol per unit mass of solvent) of solute, 1, substrate, p, unbound solute and supporting electrolyte, 3.
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Kinetics of iron oxidation upon polyphenol binding

Dalton Transactions, 2010
Polyphenol prevention of iron-mediated DNA damage occurs primarily through iron binding. Once bound, iron in the Fe(2+)-polyphenol complex autooxidizes to Fe(3+) in the presence of O(2). To determine the correlation between the rate of Fe(2+)-polyphenol autooxidation and polyphenol antioxidant ability, kinetic studies at pH = 6.0 in the presence of ...
Nathan R, Perron, Hsiao C, Wang, Sean N, Deguire, Michael, Jenkins, Mereze, Lawson, Julia L, Brumaghim   +5 more
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Kinetics of Drug Binding and Residence Time

Annual Review of Physical Chemistry, 2019
The kinetics of drug binding and unbinding is assuming an increasingly crucial role in the long, costly process of bringing a new medicine to patients. For example, the time a drug spends in contact with its biological target is known as residence time (the inverse of the kinetic constant of the drug-target unbinding, 1/ koff).
Bernetti M., Rocchia W., Masetti, Matteo, Cavalli, Andrea   +3 more
openaire   +3 more sources

Reflections on the kinetics of substrate binding

Biophysical Chemistry, 1987
The principle questions which are still being asked about enzyme-substrate complex formation are examined. Data for the maximum rates of collision complex formation are reviewed. The limitations of past experimental procedures and the potentialities of new approaches are discussed together with methods that allow the distinction between collision ...
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Binding kinetics in drug discovery

Drug Discovery Today: Technologies, 2015
Xavier, Barril, Helena, Danielsson
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Metabolic Kinetics of Nonproductive Binding Inhibition

Journal of Pharmaceutical Sciences, 1994
T, Funaki, H, Fukazawa, I, Kuruma
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Receptor Binding Kinetics

2023
openaire   +1 more source

Kinetics of cyanide binding by lactoperoxidase

Biochemistry, 1968
D, Dolman, H B, Dunford, D M, Chowdhury, M, Morrison   +3 more
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New approaches for computing ligand-receptor binding kinetics.

Current Opinion in Structural Biology, 2018
Neil J. Bruce, Gaurav K. Ganotra, D. Kokh, S. Sadiq, Rebecca C. Wade, Rebecca C. Wade, Rebecca C. Wade   +6 more
semanticscholar   +1 more source